RNA aptamers that are closely related and share a common scaffold can readily adapt to recognize new ligands through changes in just a few nucleotides.

A riboswitch class has been discovered for phosphoribosyl pyrophosphate, the biochemical precursor of nucleotides, and this novel RNA sensor commonly operates in tandem with a guanine aptamer to function like a Boolean logic gate.

RNA structures called tandem riboswitches allow bacteria to employ complex logical operations in response to nutrient starvation.

Many bacteria use a tiny riboswitch aptamer to sense the thiamin precursor HMP-PP to regulate the production of another thiamin precursor HET-P to efficiently biosynthesize this essential coenzyme.

The zinc finger protein Nerfin-1 represses the transcriptional output of Hippo signaling in cell competition by binding to the TEA DNA-binding domain of Scalloped.

Enterococci faecium encodes unique peptidoglycan composition and remodeling activity that activates host immunity.

Neural circuit monitoring and manipulation reveal that neurons of the rostral intralaminar nuclei of the thalamus projecting to the dorsal striatum activate at movement initiation and reward to reinforce actions.

A geographically and temporally restricted genomic surveillance study concludes that Enterobacterales plasmid dissemination between human and non-human niches might be occurring at greater rates than previously estimated.