The Reproducibility Project: Cancer Biology is an initiative to independently replicate selected results from a number of high-profile papers in the field of cancer biology. For each paper a Registered Report detailing the proposed experimental designs and protocols for the replications is peer reviewed and published prior to data collection; the results of these experiments are then published as a Replication Study. The project is a collaboration between the Center for Open Science and Science Exchange.
The aim of the project is two-fold: to provide evidence about reproducibility in preclinical cancer research, and to identify the factors that influence reproducibility more generally. Interpreting the results reported in the Replication Studies requires a nuanced approach, as explained in this Editorial. To date four of the studies have reproduced important parts of the original papers, one study has not, and another two studies could not be interpreted.
Roger DavisReviewing Editor
Christopher GlassReviewing Editor
Joan MassaguéReviewing Editor
Duojia PanReviewing Editor
Chi Van DangReviewing Editor