Browse our latest Cancer Biology articles

Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26^-CD35⁺ healthy stem cells and CD26⁺CD35^- CML stem cells, and how the ratio between these impacts TKI response.

A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.

A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.

The integration of pHLA binding and pHLA-TCR analysis effectively improves the precision of insilico neoantigen prioritization, potentially enhancing personalized immunotherapies for colorectal cancer.

MAD1 and TPRN were identified as novel potential therapeutic targets of lung adenocarcinoma in female never-smokers from the Xuanwei area.

Pancreatic cancer-associated muscle atrophy is characterized by strong mitochondrial metabolic defects that are not limited to carbohydrate, protein, and redox metabolism, but also concern lipid and nucleic acid metabolisms.

The new cancer treatment strategy reduces the volume of mouse cutaneous squamous cell carcinoma and reverses the expression of tumor marker proteins by stimulating the production of serum-based antibodies.

Chemotherapeutics altering DNA topology evoke RNA polymerase I inhibition, rDNA damage and consequent formation of PNAs that segregate persistent rDNA lesions from the active nucleolus, with implications for rDNA maintenance and design of new cancer treatment strategies targeting rDNA repair.

EPIC-ATAC accurately quantifies cell-type heterogeneity in tumor bulk ATAC-Seq samples using reliable cell-type specific chromatin accessibility markers for the major cell types found in tumor microenvironments.