Cancer Biology

Latest articles

1. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Cancer: Reading the DNA of telomeres

   Shamayita Roy, Claus M Azzalin

   Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.
2. 1. Cancer Biology

   A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning

   Kailai Li, Junyi Liang ... Hui Meng

   A machine learning-derived multi-gene score effectively predicts radiation sensitivity in nasopharyngeal carcinoma by integrating immune characteristics and radiosensitivity-related pathways.
3. 1. Cancer Biology

   Single-cell dissection of prognostic architecture and immunotherap response in Helicobacter pylori infection-associated gastric cancer

   Xin Zhang, Guangyu Zhang ... Chunjie Liu

   iCAF-mediated immune escape and promoted tumor angiogenesis via VEGFA/B-VEGFR1 pathway indicate that a combination of immunotherapies and anti-angiogenic targeted therapy may be effective for H. pylori infection-associated gastric cancer.
4. 1. Cancer Biology
   2. Cell Biology

   RUNX2 isoform II protects cancer cells from ferroptosis and apoptosis by promoting PRDX2 expression in oral squamous cell carcinoma

   Junjun Huang, Rong Jia, Jihua Guo

   Upregulated by HOXA10, RUNX2 isoform II transactivates PRDX2 expression and inhibits ferroptosis and apoptosis in oral squamous cell carcinoma.
5. 1. Cancer Biology

   PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

   Jiongke Wang, Yujie Shi ... Qianming Chen
6. 1. Computational and Systems Biology
   2. Cancer Biology

   BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment

   Emilio Rios-Jimenez, Anoek Zomer ... Maria Alieva
7. 1. Cell Biology
   2. Cancer Biology

   PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis

   Hairui Su, Yong Sun ... Xinyang Zhao
8. 1. Cancer Biology

   Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab-resistant HER2-positive breast cancer

   Yijia Hua, Ningjun Duan ... Yongmei Yin

   Targeting cysteine metabolism could provide novel strategies for treating trastuzumab-resistant HER2-positive breast cancer.
9. 1. Cancer Biology

   Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition

   Laleh S Arabanian, Jenni Adamsson ... Claes M Gustafsson
10. 1. Cancer Biology
    2. Cell Biology

    Image-based identification and isolation of micronucleated cells to dissect cellular consequences

    Lucian DiPeso, Sriram Pendyala ... Emily M Hatch

    The development of an automated micronucleus segmentation program enables population-level comparisons between cells with and without micronuclei and defines a highly limited response to micronucleus formation or rupture.