Browse our latest Cell Biology articles

Page 140 of 320
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs

    Qiuying Liu, Xiaoli Chen ... Wenqian Hu
    Repressing the conserved pro-differentiation let-7 microRNAs through limiting Ago2 levels is critical to maintaining pluripotency in stem cells.
    1. Cell Biology

    In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish

    Zherui Xiong, Harriet P Lo ... Thomas E Hall
    BLITZ system enables proximity-dependent biotin labelling in live zebrafish embryos with cell and tissue specificity, providing a versatile and valuable tool for proteomic discovery using the zebrafish model.
    1. Cell Biology
    2. Developmental Biology

    Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription

    Sherzod A Tokamov, Ting Su ... Richard G Fehon
    Kibra-mediated Hippo complex assembly promotes Kibra degradation in a negative feedback loop that is regulated by mechanical tension.
    1. Cell Biology
    2. Evolutionary Biology

    A flagellate-to-amoeboid switch in the closest living relatives of animals

    Thibaut Brunet, Marvin Albert ... Nicole King
    The closest living relatives of animals, the choanoflagellates, switch from a flagellate to an amoeboid phenotype under confinement.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets

    Valeria Zoni, Rasha Khaddaj ... Stefano Vanni
    In parallel to protein-driven processes, characteristic physicochemical properties of the endoplasmic reticulum membrane modulate intracellular fat accumulation and lipid droplet formation.
    1. Cell Biology
    2. Developmental Biology

    Rab5 and Rab11 maintain hematopoietic homeostasis by restricting multiple signaling pathways in Drosophila

    Shichao Yu, Fangzhou Luo, Li Hua Jin
    Rab5 and Rab11 regulate hematopoietic homeostasis in Drosophila, and this process involves the JNK, Toll, and Ras/EGFR signaling pathways and autophagy.
    1. Cell Biology
    2. Developmental Biology

    Visualizing the metazoan proliferation-quiescence decision in vivo

    Rebecca C Adikes, Abraham Q Kohrman ... David Q Matus
    During organismal development, CDK activity at mitotic exit is predictive of future cell behavior, indicating whether a cell will divide again or enter a quiescent state.
    1. Cell Biology
    2. Developmental Biology

    Cell Cycle: Deciding when to exit

    Joy H Meserve, Robert J Duronio
    A new imaging approach can distinguish between cells destined to stop proliferating and those committed to re-entering the cell cycle in live animals.
    Version of Record
    Insight
    1. Cell Biology
    2. Genetics and Genomics

    Aging: Unite to predict

    Meeraj Kothari, Daniel W Belsky
    Integrating the analysis of molecular data from different sources may improve our understanding of the effects of biological aging.
    Version of Record
    Insight
    1. Cell Biology

    Generation of stress fibers through myosin-driven reorganization of the actin cortex

    Jaakko I Lehtimäki, Eeva Kaisa Rajakylä ... Pekka Lappalainen
    Live-cell microscopy studies revealed that stress fibers can be generated de novo from the actin cortex without the involvement of stress fiber precursors.