Browse our latest Cell Biology articles

Page 145 of 333
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

    Wan Hua Li, Ke Huang ... Yong Juan Zhao
    The first-in-class cell-permeant fluorescent probe provides direct and visual evidence of SARM1 activation in axonal degeneration and identified the first covalent, allosteric inhibitor of SARM1 acting on the NAD-binding pocket in the ARM domain.
    1. Cell Biology
    2. Computational and Systems Biology

    Artistoo, a library to build, share, and explore simulations of cells and tissues in the web browser

    Inge MN Wortel, Johannes Textor
    By letting users build interactive simulations directly in a web browser, Artistoo unlocks new ways to communicate, teach, and collaborate in computational biology research.
    1. Cell Biology

    A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression

    Dianrong Li, Jie Chen ... Xiaodong Wang
    A phosphorylation of receptor interacting RIPK3 switches its pro-necroptosis function to apoptosis that promotes luteal regression which induced by Prostaglandin F2alpha.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Design principles of the ESCRT-III Vps24-Vps2 module

    Sudeep Banjade, Yousuf H Shah ... Scott D Emr
    Laterally associating specific ESCRT-III subunits can replace one another with simple modifications, providing insights into the design principles of ESCRT-III heteropolymerization.
    1. Cell Biology

    The Nesprin-1/-2 ortholog ANC-1 regulates organelle positioning in C. elegans independently from its KASH or actin-binding domains

    Hongyan Hao, Shilpi Kalra ... Daniel A Starr
    The giant KASH protein ANC-1 maintains the integrity of the cytoplasm to anchor nuclei, ER, and other organelles within the cell.
    1. Cell Biology
    2. Neuroscience

    Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction

    Xingyu Zhang, Li Zou ... Zhentao Zhang
    Amphiphysin I is identified as a new substrate of AEP, and the resultant fragment induces synaptic dysfunction and promotes tau hyperphosphorylation via activating CDK5 kinase.
    1. Cell Biology

    Cellular Organisation: Putting organelles in their place

    Patricia Ulm, Verena Jantsch
    Experiments in C. elegans reveal new insights into how the ANC-1 protein helps to anchor the nucleus and other organelles in place.
    Version of Record
    Insight
    1. Cell Biology

    Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever

    Takeshi Yoneshiro, Naoya Kataoka ... Shingo Kajimura
    Genetic and cellular studies in rodents found branched-chain amino acids are critical nutrients that are transported and oxidized in the mitochondria through their carrier MBC for optimal febrile responses.
    1. Cell Biology

    Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology

    Rohini R Nair, Dmitry Zabezhinsky ... Jeffrey E Gerst
    Prokaryotes use polycistronic messages for coordinated translation, whereas eukaryotic cells may achieve tunable protein synthesis by packaging monocistronic mRNAs into functional multiplexes via co-transcriptional interallelic coupling and non-canonical histone-H4 functions.
    1. Cell Biology
    2. Physics of Living Systems

    Cell-scale biophysical determinants of cell competition in epithelia

    Daniel Gradeci, Anna Bove ... Guillaume Charras
    Mechanical competition is controlled by biophysical parameters that regulate cellular homeostatic density, while biochemical competition is regulated by parameters that influence the organisation of cells in a tissue.