Browse our latest Cell Biology articles

Page 144 of 320
    1. Cell Biology
    2. Physics of Living Systems

    Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

    James F Pelletier, Christine M Field ... Timothy J Mitchison
    Live imaging of multiple cytoplasmic networks in frog egg extracts calls for new models for how egg cytoplasm is physically organized during cleavage divisions.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes

    Steffen Preissler, Claudia Rato ... David Ron
    Regulation of the endoplasmic reticulum chaperone BiP by calcium.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Cardiac endothelial cells maintain open chromatin and expression of cardiomyocyte myofibrillar genes

    Nora Yucel, Jessie Axsom ... Zoltan Arany
    Endothelial cells in the heart have transcriptional and epigenetic signatures of cardiomyocytes.
    1. Cell Biology
    2. Medicine

    An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

    Hong Wang, Xueping Wan ... Libin Liu
    A non-canonical p53 function in adipocyte plays a critical role in energy homeostasis and is involved in obesity-associated metabolic dysfunctions.
    1. Cell Biology
    2. Neuroscience

    TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

    Kathleen M Cunningham, Kirstin Maulding ... Thomas E Lloyd
    Impaired nuclear import of the transcription factor TFEB/MITF is a major cause of autophagy and lysosome dysfunction in amyotrophic lateral sclerosis caused by mutations in the C9orf72 gene.
    1. Cell Biology
    2. Genetics and Genomics

    A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

    Dana M Talsness, Katie G Owings ... Clement Y Chow
    An ion transporter is hyperglycosylated and 50% less functional in NGLY1-deficient cells, potentially explaining several symptoms of NGLY1 deficiency such as lack of sweat and tears.
    1. Cell Biology
    2. Developmental Biology

    Epidermal PAR-6 and PKC-3 are essential for larval development of C. elegans and organize non-centrosomal microtubules

    Victoria G Castiglioni, Helena R Pires ... Mike Boxem
    PAR-6 and PKC-3/aPKC are essential for postembryonic development of C. elegans and control the organization of non-centrosomal microtubule bundles in the epidermis, likely through recruitment of NOCA-1/Ninein.
    1. Cell Biology
    2. Computational and Systems Biology

    The nucleus serves as the pacemaker for the cell cycle

    Oshri Afanzar, Garrison K Buss ... James E Ferrell Jr
    Just as the sinoatrial node acts as pacemaker for the heart, the nucleus acts as pacemaker for the Xenopus embryonic cell cycle.
    1. Cell Biology
    2. Medicine

    MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice

    Shilpak Bele, Shravan Babu Girada ... Prasenjit Mitra
    Class 1 histone deacetylase (HDAC) inhibitor MS-275 enhances the efficacy of glucagon-like peptide 1 receptor (GLP-1R) therapy for glycemic control and reduction of obesity.
    1. Cell Biology

    Conformation of the nuclear pore in living cells is modulated by transport state

    Joan Pulupa, Harriet Prior ... Sanford M Simon
    Polarized fluorescence microscopy of individual nuclear pores in vivo reveals conformational changes in select domains of proteins of the inner ring.