Browse our latest Cell Biology articles

Page 151 of 333
    1. Cell Biology
    2. Neuroscience

    Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR

    Javier Emperador-Melero, Giovanni de Nola, Pascal S Kaeser
    Leukocyte common antigen-related receptor protein tyrosine phosphatases (LAR-RPTPs) are precisely localized to synaptic appositions, but do not control the assembly and function of the presynaptic nerve terminal.
    1. Cell Biology
    2. Plant Biology

    Stretch-activated ion channels identified in the touch-sensitive structures of carnivorous Droseraceae plants

    Carl Procko, Swetha Murthy ... Joanne Chory
    Identification of putative mechanisms for mechanosensation-dependent prey capture in carnivorous plants.
    1. Cell Biology
    2. Neuroscience

    Latrophilin GPCR signaling mediates synapse formation

    Richard Sando, Thomas C Südhof
    Spatial restriction of GPCR signaling at nascent synapses by adhesion complexes drives excitatory synapse formation and specificity in the hippocampus.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

    Lorraine De Jesús-Kim, Larry J Friedman ... Stephen P Bell
    A multi-step process of helicase activation sensitizes replication initiation to the extent of replicative helicase phosphorylation.
    1. Cell Biology
    2. Neuroscience

    Ciliary neuropeptidergic signaling dynamically regulates excitatory synapses in postnatal neocortical pyramidal neurons

    Lauren Tereshko, Ya Gao ... Piali Sengupta
    Neuropeptidergic signaling via cilia-localized receptors dynamically regulates excitatory synaptic drive in postnatal rat neocortical pyramidal neurons.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Reformulation of an extant ATPase active site to mimic ancestral GTPase activity reveals a nucleotide base requirement for function

    Taylor B Updegrove, Jailynn Harke ... Kumaran S Ramamurthi
    Reengineering the nucleotide-binding pocket of an extant ATPase to restore ancestral GTPase activity revealed an ATP-dependent intermediate required for function and suggested why the protein evolved to use ATP.
    1. Cell Biology
    2. Immunology and Inflammation

    Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism

    Leonie Zeitler, Alessandra Fiore ... Peter J Murray
    IL4i1 is an amino acid oxidase expressed in the mammalian immune system and snake venoms, which control diametrically opposite cell protection versus cell death pathways, respectively.
    1. Cell Biology
    2. Neuroscience

    TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells

    Kae-Jiun Chang, Ira Agrawal ... Jonah R Chan
    Glial TDP-43 regulates splicing and expression of neurofascin and is required for proper assembly and maintenance of paranodal axoglial junctions.
    1. Cell Biology
    2. Neuroscience

    Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation

    Amanjot Singh, Joern Hulsmeier ... Baskar Bakthavachalu
    Ataxin-2 interacts with neuronal mRNA in RNP granules.
    1. Cell Biology
    2. Neuroscience

    Bidirectional regulation of glial potassium buffering – glioprotection versus neuroprotection

    Hailun Li, Lorenzo Lones, Aaron DiAntonio
    A neuromodulatory circuit bidirectionally regulates the glial capacity to buffer ions and water in response to changes in neuronal excitation in order to balance glial versus neuronal protection.