Browse our latest Cell Biology articles

Page 23 of 325
    1. Cell Biology
    2. Medicine

    Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

    Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
    Transition from healthy to diseased state is a cell-type-specific process, influenced by neighboring cells and resulting in functionally meaningful differences between pulmonary artery adventitial fibroblasts and smooth muscle cells.
    1. Cell Biology
    2. Medicine

    Pulmonary Hypertension: When cell teamwork turns toxic

    Wadih EI Khoury, Stephen Y Chan
    In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.
    Version of Record
    Insight
    1. Cancer Biology
    2. Cell Biology

    Cytosolic and endoplasmic reticulum chaperones inhibit wt-p53 to increase cancer cells' survival by refluxing ER-proteins to the cytosol

    Salam Dabsan, Gali Zur ... Aeid Igbaria
    Identifying the regulators of a non-genetic mechanism (ERCYS) that is constitutively activated in cancer cells to provide pro-survival properties.
    1. Cancer Biology
    2. Cell Biology

    N6-methyladenosine in DNA promotes genome stability

    Brooke A Conti, Leo Novikov ... Mariano Oppikofer
    Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.
    1. Cell Biology

    Stratification of enterochromaffin cells by single-cell expression analysis

    Yan Song, Linda J Fothergill ... Gene W Yeo
    Molecularly defined serotonin (enterochromaffin) cells of the gut lining were distinguished by single-cell expression analysis, in situ hybridization, and immunohistochemistry into 14 topographically organized clusters, with features implying that they are functionally distinct classes of serotonin cells.
    1. Cell Biology

    Small-molecule activation of TFEB alleviates Niemann–Pick disease type C via promoting lysosomal exocytosis and biogenesis

    Kaili Du, Hongyu Chen ... Dan Li
    Small-molecule agonists of transcription factor EB alleviate Niemann–Pick disease type C via promoting lysosomal function.
    1. Cell Biology
    2. Developmental Biology

    Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    • Inadequate
    1. Cell Biology

    The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods

    Ziv Yaniv, Ifeanyichukwu U Anidi ... Andrea J Radtke
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Lens Development: Bringing signaling complexity into focus

    Sarah Y Coomson, Salil A Lachke
    A study in mice reveals key interactions between proteins involved in fibroblast growth factor signaling and how they contribute to distinct stages of eye lens development.
    Version of Record
    Insight
    1. Cell Biology
    2. Evolutionary Biology

    Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

    Paul Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson
    Fitness defects arising from deletion of the gene encoding the bacterial equivalent of actin (mreB) are readily compensated by mutations affecting cell wall synthesis.