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Page 24 of 314
    1. Cell Biology

    The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy

    Yutaro Hama, Yuko Fujioka ... Nobuo N Noda
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia

    Xiaojiao Hua, Chen Zhao ... Yan Zhou
    An enhancer-dependent transcriptional machinery finely tunes the expression of Ctnnb1 in intestinal crypts, thereby balancing homeostasis and tumorigenesis of intestinal epithelia.
    1. Cell Biology
    2. Neuroscience

    Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency

    Apostolos Papandreou, Nivedita Singh ... Robin Ketteler
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    Arpin deficiency increases actomyosin contractility and vascular permeability

    Armando Montoya-Garcia, Idaira M Guerrero-Fonseca ... Michael Schnoor
    Arpin regulates actomyosin contractility and endothelial barrier integrity by controlling the activity of the kinases ROCK1 and ZIPK, but not Arp2/3.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins

    Kristina Ehring, Sophia Friederike Ehlers ... Kay Grobe
    A composite hedgehog release model that incorporates and supports a previously disparate set of observations has been presented.
    1. Cell Biology

    WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signaling

    Ankita B Jaykumar, Derk Binns ... Melanie H Cobb
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Reactive oxygen species suppress phagocyte surveillance by oxidizing cytoskeletal regulators

    Iuliia Ferling, Steffen Pfalzgraf ... Spencer A Freeman
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Point of View: Teaching troubleshooting skills to graduate students

    Gina Partipilo, Yang Gao ... Benjamin K Keitz
    Pipettes and Problem Solving is an initiative that teaches some of the skills needed to figure out why an experiment is producing unexpected results.
    1. Cell Biology

    Kidney Fibrosis: Lock out SIRT4

    Kaiqiang Zhao, Zhongjun Zhou
    The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
    Version of Record
    Insight
    1. Cell Biology
    2. Neuroscience

    CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function

    Longxin Xie, Jessica Merjane ... Christopher J Donnelly
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
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