Dharmendra Kumar Nath, Subash Dhakal, Youngseok Lee
TRPγ is essential for maintaining lipid homeostasis in Drosophila melanogaster, linking neuronal regulation to fat metabolism and suggesting potential therapeutic avenues for metabolic disorders.
The established under-flow migration tracker (UFMTrack) framework allows for automated and scalable studies of immune cell interactions with and extravasation across endothelial monolayer under flow in vitro.
Artem K Velichko, Nadezhda V Petrova ... Omar L Kantidze
Treacle condensation, driven by alternating charge blocks, facilitates interactions with transcription factors to spatially segregate ribosomal RNA synthesis and processing, while also recruiting TOPBP1 for activation of the rDNA damage response.
Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
Transition from healthy to diseased state is a cell-type-specific process, influenced by neighboring cells and resulting in functionally meaningful differences between pulmonary artery adventitial fibroblasts and smooth muscle cells.
Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.