Browse our latest Cell Biology articles

Page 254 of 315
    1. Cell Biology
    2. Developmental Biology

    Physical association between a novel plasma-membrane structure and centrosome orients cell division

    Takefumi Negishi, Naoyuki Miyazaki ... Naoto Ueno
    A newly discovered membrane structure associates with one of the centrioles and affects two important centrosomal events in epidermal cells – ciliary positioning and spindle orientation – through a physical interaction.
    1. Cell Biology
    2. Neuroscience

    Proneurotrophin-3 promotes cell cycle withdrawal of developing cerebellar granule cell progenitors via the p75 neurotrophin receptor

    Juan Pablo Zanin, Elizabeth Abercrombie, Wilma J Friedman
    The p75 neurotrophin receptor regulates when granule neuron progenitors exit the cell cycle in the developing cerebellum.
    1. Cell Biology
    2. Genetics and Genomics

    A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

    Maulik R Patel, Ganesh K Miriyala ... Harmit S Malik
    A 'male-harming' mtDNA mutation has been identified in Drosophila and impairs male fertility without impairing other male or female functions.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity

    Richard Panayiotou, Francesc Miralles ... Richard Treisman
    G-actin binding controls the susceptibility of MRTF-A to phosphorylation, which works in concert with multiple NES elements to regulate MRTF-A subcellular localisation and activity.
    1. Cancer Biology
    2. Cell Biology

    Different promoter affinities account for specificity in MYC-dependent gene regulation

    Francesca Lorenzin, Uwe Benary ... Elmar Wolf
    Differences in promoter affinity and MYC levels explain distinct expression profiles induced by physiological and oncogenic MYC.
    1. Cancer Biology
    2. Cell Biology

    Mathematical Modeling: Tuning the MYC response

    Ying Zheng, David Levens
    Version of Record
    Insight
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition

    Maud Magdeleine, Romain Gautier ... Bruno Antonny
    The golgin GMAP-210 captures vesicles at the cis Golgi by merely recognizing the high curvature and lipid unsaturation level of transport vesicles.
    1. Cell Biology
    2. Computational and Systems Biology

    Global, quantitative and dynamic mapping of protein subcellular localization

    Daniel N Itzhak, Stefka Tyanova ... Georg HH Borner
    A spatial proteomics method can capture physiological protein subcellular localization changes in response to a stimulus, resolving all major organelles.
    1. Cell Biology
    2. Neuroscience

    Reconstruction of genetically identified neurons imaged by serial-section electron microscopy

    Maximilian Joesch, David Mankus ... Joshua R Sanes
    A new pipeline of electron microscopy techniques reduces the time required to visualize genetically targeted neurons and their connections by two orders of magnitude.
    1. Cell Biology

    Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors

    Kenta Yamamoto, Jiguang Wang ... Shan Zha
    Orphan ATM kinase-domain missense mutations are unexpectedly common and form a potent oncogenic event and a biomarker for Topo-isomerase I inhibitor based therapy.