Browse our latest Cell Biology articles

Page 259 of 316
    1. Cell Biology

    A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes

    Yuliya Gryaznova, Ayse Koca Caydasi ... Gislene Pereira
    Daughter-cell-associated factors and centrosome-based regulation is important in mitotic exit and spindle position checkpoint control.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle

    Ruzbeh Mosadeghi, Kurt M Reichermeier ... Radoslav I Enchev
    The general principles that underlie the mechanism of action of the COP9-Signalosome, a key regulator of the largest family of ubiquitin ligase enzymes in human cells, have been identified using structural and kinetic techniques.
    1. Cell Biology

    Spatial organization shapes the turnover of a bacterial transcriptome

    Jeffrey R Moffitt, Shristi Pandey ... Xiaowei Zhuang
    Transcriptome-scale RNA imaging and lifetime measurements reveal that the E. coli transcriptome is spatially organized and that this organization modulates the post-transcriptional fate of bacterial mRNAs.
    1. Cell Biology
    2. Neuroscience

    Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines

    Sonia Afroz, Julie Parato ... Sheryl Sue Smith
    Extrasynaptic GABAA receptors that emerge at puberty trigger adolescent synaptic pruning; pruning is prevented and cognition is impaired if the receptors are absent.
    1. Cell Biology
    2. Computational and Systems Biology

    Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation

    John M Ankers, Raheela Awais ... Michael RH White
    Cell imaging and mathematical modelling show reciprocal cross-regulation between inflammatory signalling and cell cycle timing, which is mediated through functional interactions between NF-B and E2F proteins.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

    Madlen Matz-Soja, Christiane Rennert ... Rolf Gebhardt
    The Hedgehog signalling pathway is a master regulator of lipid metabolic processes and their zonation in the adult liver of mice and humans.
    1. Cell Biology

    ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion

    Amy J Curwin, Nathalie Brouwers ... Vivek Malhotra
    The release of Acb1 protein from yeast cells requires the ESCRT-III complex to stabilize the compartment for unconventional protein secretion (CUPS).
    1. Cell Biology

    α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism

    Amin Khalifeh-Soltani, Arnold Ha ... Kamran Atabai
    The milk protein Mfge8 promotes fat uptake and slows gastrointestinal motility to optimize nutrient absorption.