Browse our latest Cell Biology articles

Page 258 of 316
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer

    Karthikeyani Chellappa, Poonamjot Deol ... Frances M Sladek
    Proper gut health depends on the balance between two naturally occurring variants of a transcription factor in the colon.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    A feedback amplification loop between stem cells and their progeny promotes tissue regeneration and tumorigenesis

    Jun Chen, Na Xu ... Rongwen Xi
    A newly discovered feedback amplification loop between stem cells and their immediate daughter progenitor cells drives epithelial regeneration and tumor development.
    1. Cell Biology
    2. Immunology and Inflammation

    Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells

    Nimi Marcel, Apurva Sarin
    Notch1 activates autophagy to regulate the survival of T-regulatory cells from mice.
    1. Cell Biology

    Mitochondria: Selective protein degradation ensures cellular longevity

    Sandra Malmgren Hill, Thomas Nyström
    Version of Record
    Insight
    1. Cell Biology

    Selective sorting and destruction of mitochondrial membrane proteins in aged yeast

    Adam L Hughes, Casey E Hughes ... Daniel E Gottschling
    A new mitochondrial protein degradation pathway selectively sorts and destroys a subset of the mitochondrial membrane proteome to protect mitochondria in times of stress.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias

    Bradford M Stubenhaus, John P Dustin ... Jason Pellettieri
    Physiological porphyrin biosynthesis causes photosensitivity in fasted planarians, providing an experimentally tractable animal model of acute porphyrias.
    1. Cell Biology

    Spatial signals link exit from mitosis to spindle position

    Jill Elaine Falk, Dai Tsuchiya ... Angelika Amon
    In yeast, exit from mitosis is triggered by the movement of one spindle pole body out of the mother cell into the bud, the future daughter cell.
    1. Cell Biology

    An extensive program of periodic alternative splicing linked to cell cycle progression

    Daniel Dominguez, Yi-Hsuan Tsai ... Zefeng Wang
    Extensive periodic regulation of alternative splicing during the cell cycle in genes is linked to cell cycle functions, and involves an auto-inhibitory mechanism that uses the protein kinase CLK1.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The glyoxylate shunt is essential for desiccation tolerance in C. elegans and budding yeast

    Cihan Erkut, Vamshidhar R Gade ... Teymuras V Kurzchalia
    Roundworms and yeast can survive extreme desiccation only by switching their metabolism into a gluconeogenic mode and producing very high amounts of trehalose via the glyoxylate shunt.
    1. Cell Biology
    2. Neuroscience

    The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling

    Kathryn P Harris, Yao V Zhang ... J Troy Littleton
    Syntaxin 4 regulates retrograde signaling in the postsynaptic compartment at Drosophila synapses by controlling trafficking of Neuroligin and Synaptotagmin 4 cargo.