Browse our latest Cell Biology articles

Page 292 of 316
    1. Cell Biology

    Potassium dependent rescue of a myopathy with core-like structures in mouse

    M Gartz Hanson, Jonathan J Wilde ... Lee Niswander
    A mouse model of human muscle myopathy is used to provide mechanistic insight, identify possible biomarkers of disease, and suggest possible therapeutic strategies to alleviate muscle weakness.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF

    Guo Cheng, Ming Zhong ... Hui Sun
    Two membrane proteins that belong to a new type of cell-surface receptor mediate the transmembrane signaling for a secreted factor that has broad therapeutic value.
    1. Cell Biology

    Mapping the dynamics of force transduction at cell–cell junctions of epithelial clusters

    Mei Rosa Ng, Achim Besser ... Gaudenz Danuser
    The integrated quantification of spontaneous dynamic cell-cell force transmissions at both multi-cellular and subcellular scales enables spatiotemporal correlations of stress distribution with biomolecules in small cell clusters.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

    Angela Castanieto, Michael J Johnston, Todd G Nystul
    The specification of cell polarity is essential for self-renewal and the segregation of stem-cell and daughter-cell fates in an epithelial stem cell lineage.
    1. Cell Biology

    Controlling fertilization and cAMP signaling in sperm by optogenetics

    Vera Jansen, Luis Alvarez ... Dagmar Wachten
    Optogenetics is a non-invasive way to study cAMP signaling in sperm cells, which is able to control sperm motility and fertilization.
    1. Cell Biology
    2. Developmental Biology

    Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

    Jennifer T Wang, Jarrett Smith ... Geraldine Seydoux
    The MEG (maternal-effect germline defective) proteins, MEG-1, 2, 3 and 4, regulate RNA granule dynamics in vivo.
    1. Cell Biology
    2. Developmental Biology

    Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity

    Hirohito Shimizu, Johann Schredelseker ... Jau-Nian Chen
    Enhancing mitochondrial Ca2+ uptake effectively suppresses aberrant Ca2+ induced arrhythmogenic events in zebrafish, mouse and human cardiomyocytes, demonstrating a critical role for mitochondria in the regulation of cardiac rhythmicity.
    1. Physics of Living Systems
    2. Cell Biology

    Mechanical design principles of a mitotic spindle

    Jonathan J Ward, Hélio Roque ... François Nédélec
    Precise control of microtubule architecture greatly increases the force that the spindle can exert on chromosomes.
    1. Cell Biology
    2. Developmental Biology

    Cis-interactions between Notch and its ligands block ligand-independent Notch activity

    William Hunt Palmer, Dongyu Jia, Wu-Min Deng
    Notch ligands expressed in the same cell as the Notch receptor are crucial to prevent accidental, ligand-independent Notch activity.
    1. Cell Biology
    2. Neuroscience

    Astrocytes refine cortical connectivity at dendritic spines

    W Christopher Risher, Sagar Patel ... Cagla Eroglu
    Spines with multiple excitatory contacts are potential sites for competition between thalamic and cortical axons, which is regulated by the astrocytes through the secreted synaptogenic protein hevin.