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MiR 204/211 antagonize synovial inflammation and hyperproliferation by regulation of its downstream target gene Ssrp1, and decelerated RA progression.

The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.

A critical role of aCT in the distinct activation mechanism of insulin receptor and insulin-like growth factor 1 receptor.

Human GDOWN1 is identified as an extremely tightly controlled nucleocytoplasmic shuttling protein, and its translocation into the nucleus plays a crucial role in modulating the global transcription and facilitating the cellular adaptation to certain stresses.

ABHD16A is a phospholipid-modifying endoplasmic reticulum (ER) membrane protein required for both mitochondrial fission and fusion machinery recruitment to ER-associated mitochondrial constrictions.

Erythroid maturation-dependent remodelling of CTLH E3 complex, along with its cognate E2, controls the orderly progression of human erythropoiesis, thus establishing a paradigm for other E2-E3 ubiquitylation modules involved in developmental processes.

In vivo live imaging reveals the trafficking dynamics of three cellular organelles in neocortical axons with single vesicle resolution and demonstrates activity-dependent changes.

Cholesterol plays an essential role in hair bundles, and Kiaa1024L/Minar2 regulates cholesterol distribution and homeostasis to ensure normal hearing.

A systemic feature of idiopathic pulmonary fibrosis whereby urine-derived exosomes contain pro-fibrotic microRNAs and interfere with response to tissue injury.

Cryo-electron microscopy can be used to detect biomolecules in entire 100- to 250-nm-thick cell slices when using a method to collect montages that prevents radiation damage in areas that have not been imaged yet.