Browse our latest Cell Biology articles

Page 8 of 317
    1. Cell Biology
    2. Cancer Biology

    Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

    David Papadopoli, Ranveer Palia ... Ivan Topisirovic
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response

    Akinori Endo, Chikage Takahashi ... Yukiko Yoshida
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    Monocyte-derived macrophage recruitment mediated by TRPV1 is required for eardrum wound healing

    Yunpei Zhang, Pingting Wang ... Xiaorui Shi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress

    Rezwana Karim, Wendi Teng ... Hening Lin
    A cross-talk is revealed between two branches of metabolisms, amino acid limitation suppressing fatty acid biosynthesis, via posttranslational modifications of an enzyme involved in fatty acid biosynthesis.
    1. Cell Biology

    MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio

    Peipei Xu, Rui Zhang ... Wenxiang Meng
    MARK2-mediated phosphorylation of CAMSAP2 dynamically controls Golgi orientation by altering microtubule anchoring and polarity during directional cell migration.
    1. Cell Biology

    Reprograming gene expression in ‘hibernating’ C. elegans involves the IRE-1/XBP-1 pathway

    Melanie Lianne Engelfriet, Yanwu Guo ... Rafal Ciosk
    Gene expression in nematodes during cold-induced dormancy is proposed to be regulated at the transcription level, partly involving the activation of unfolded protein response (UPR) through the IRE-1/XBP-1 signaling pathway.
    1. Cell Biology

    Emergence of Dip2-mediated specific DAG-based PKC signalling axis in eukaryotes

    Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
    Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in eukaryotes.
    1. Cell Biology
    2. Developmental Biology

    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

    Qian Wang, Hongge Li ... Xin Zhang
    FGF signaling drives lens development by recruiting Grb2 through Shc1, Frs2, and Shp2 to regulate transcription and cytoskeletal arrangements.
    1. Cell Biology
    2. Medicine

    Disruption of the novel nested gene Aff3ir mediates disturbed flow-induced atherosclerosis in mice

    Shuo He, Lei Huang ... Jinlong He
    Endothelial-specific supplementation with Aff3ir-ORF2 significantly ameliorated disturbed flow-induced endothelial activation and the development of atherosclerotic plaques, highlighting its promising therapeutic potential for the treatment of atherosclerosis.
    1. Cell Biology
    2. Developmental Biology

    Cell Signaling: Not all dimers are equal

    Jeet H Patel, Mary C Mullins
    Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.
    Version of Record
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