Disrupting full-length BEND2 impairs ovarian reserve establishment without causing male sterility, highlighting a sex-specific role in fertility and offering new insights into genetic contributions to infertility diagnosis and reproductive health.
Glycolysis and attenuates oxidative phosphorylation through long-chain fatty acids, while mitochondrial biogenesis and anabolism remain intact, to accelerate the progression of acute megakaryocytic leukemia.
A time-course RNA-seq analysis of muscle remodeling reveals transcriptional dynamics independent of autophagy and highlights the significance of BNIP3 in mitochondrial degradation in vivo.
Hexokinases regulate the metabolic transcription factor MML-1 via distinct pathways, linking glucose metabolism and organellar signaling to longevity control in Caenorhabditis elegans and mammals.
