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Late effects of radiation therapy in mice can be prevented by treatment with either senolytics navitoclax or quercetin plus dasatinib or the senostatic metformin.

B-cell integrin co-stimulation promotes the formation of an actomyosin network that drives integrin-dependent immune synapse formation and B-cell activation.

CLUH links growth signaling pathways and mitochondrial metabolism with cell cycle progression by regulating astrin-1 synthesis and stability.

A high-throughput small molecule screen defined compounds that inactivate primary human hepatic stellate cells (HSCs) and led to the identification of nanchangmycin, which regulates intracellular Ca²⁺ levels and the activity of multiple kinases to control HSC fibrotic activity.

Metabolic supplementation attenuates age-dependent declines in regeneration.

The essential role of focal adhesion kinase in locally regulating insulin secretion and calcium responses in pancreatic beta cells is identified through the use of the pancreatic slice technique.

A genome-wide CRISPR/Cas9 knockout screening approach identified C/EBPδ as transcriptional regulator of the alarmins S100A8 and S100A9 during differentiation of monocytes and inflammatory processes in vivo.

The Ryanodine receptor type 1 calcium channels play a critical role in age-related muscle function loss.

Mathematical characterization of the shape of cellular protrusions that form cell–cell contacts in tissues reveals the parameters required for optimizing biological functional objectives, like maximizing cell–cell contact and communicating directional information.

Dopamine D1 receptor signaling from the Golgi apparatus in murine striatal medium spiny neurons is regulated by monoamine transporter OCT2.