Browse our latest Chromosomes and Gene Expression articles

Page 39 of 118
    1. Chromosomes and Gene Expression

    ZC3H4 restricts non-coding transcription in human cells

    Chris Estell, Lee Davidson ... Steven West
    An unbiased proteomics approach in human cells identifies ZC3H4 and shows that it is important for controlling the transcription of unstable RNA synthesized upstream of promoters and over enhancers.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Channel nuclear pore complex subunits are required for transposon silencing in Drosophila

    Marzia Munafò, Victoria R Lawless ... Benjamin Czech
    By linking export and licensing of a piRNA precursor transcript, channel nuclear pore complex subunits Nup54 and Nup58 are specifically required to silence transposons in the Drosophila ovary.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA

    Matthew T Parker, Katarzyna Knop ... Gordon G Simpson
    The expression of Arabidopsis NLR immune response genes is modulated by premature transcription termination, and this has implications for understanding NLR regulation and evolutionary dynamics.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

    Laura Plassart, Ramtin Shayan ... Celia Plisson-Chastang
    Cryo-EM and functional studies reveal how combined action of proteins RPS26/eS26 and RIO1 allows late precursors to the human small ribosomal particle to be matured into fully translation-competent 40S subunits.
    1. Chromosomes and Gene Expression

    Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay

    Hiroaki Tachiwana, Mariko Dacher ... Noriko Saitoh
    A new method using permeabilized cells and recombinant histones enables to analyze histone incorporations at the DNA sequence level.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity

    Rachel A Johnston, Philippe Vullioud ... Jenny Tung
    In cooperatively breeding Damaraland mole-rats, transitioning to 'queen' results in extensive gene regulatory and morphological remodeling, but also costs to skeletal integrity that scale with reproductive investment.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer

    Carter J Barger, Linda Chee ... Adam R Karpf
    FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Common virulence gene expression in adult first-time infected malaria patients and severe cases

    J Stephan Wichers, Gerry Tonkin-Hill ... Anna Bachmann
    Parasites with pathogenic variant surface antigens are common in adult malaria patients with a naive immune status.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Coordination between nucleotide excision repair and specialized polymerase DnaE2 action enables DNA damage survival in non-replicating bacteria

    Asha Mary Joseph, Saheli Daw ... Anjana Badrinarayanan
    Live-cell imaging shows that replication-independent specialized polymerase action is a consequence of lesion processing via NER and impacts cellular survival under stress outside replicative phases of the cell cycle.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A spontaneous genetically induced epiallele at a retrotransposon shapes host genome function

    Tessa M Bertozzi, Nozomi Takahashi ... Anne C Ferguson-Smith
    A retrotransposon-derived recombination event in inbred mice gives rise to an epiallele and tissue-specific phenotypes.