Browse our latest Computational and Systems Biology articles

Page 2 of 76
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2

    Bitya Raphael-Mizrahi et al.
    Osteogenic growth peptide displays agonistic activity at CB2.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

    Morten Hostrup et al.
    Global proteomic and acetylomic analyses reveal how skeletal muscle adapts to high-intensity interval training including adaptations to processes regulating metabolism and contraction.
    1. Computational and Systems Biology
    2. Neuroscience

    Electrocorticography is superior to subthalamic local field potentials for movement decoding in Parkinson’s disease

    Timon Merk et al.
    Advanced machine learning based brain signal decoding of grip-force as a proxy for movement vigor shows Parkinson's disease related performance reduction, suggestive of a loss of cortical vigor encoding in the absence of dopamine.
    1. Cancer Biology
    2. Computational and Systems Biology

    Regulation of protein complex partners as a compensatory mechanism in aneuploid tumors

    Gökçe Senger et al.
    Coordinated regulation of co-complex members compensates for aneuploidy-induced stoichiometric imbalances in human cancer.
    1. Computational and Systems Biology
    2. Ecology

    The LOTUS initiative for open knowledge management in natural products research

    Adriano Rutz et al.
    The LOTUS initiative builds, through the Wikidata knowledge graph, a virtuous cycle of data sharing practices for natural products research.
    1. Computational and Systems Biology

    Toward the cellular-scale simulation of motor-driven cytoskeletal assemblies

    Wen Yan et al.
    aLENS implements new parallel methods to resolve cytoskeletal assembly dynamics with high stability, physical consistency, and scalability.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Unifying the known and unknown microbial coding sequence space

    Chiara Vanni et al.
    A newly developed computational framework provides an overview of the extent, diversity, and relevance of the genes of unknown function in genomes and metagenomes.