Browse our latest Computational and Systems Biology articles

Page 21 of 114
    1. Computational and Systems Biology
    2. Neuroscience

    Dissecting the chain of information processing and its interplay with neurochemicals and fluid intelligence across development

    George Zacharopoulos, Francesco Sella ... Roi Cohen Kadosh
    A novel integrative biological and psychological mechanistic explanation links cognitive processes and neurotransmitters across human development and establishes their involvement in intelligent behavior.
    1. Computational and Systems Biology
    2. Neuroscience

    Dynamic organization of cerebellar climbing fiber response and synchrony in multiple functional components reduces dimensions for reinforcement learning

    Huu Hoang, Shinichiro Tsutsumi ... Keisuke Toyama
    Dimensions for reinforcement learning reduced by dynamic organization of cerebellar climbing fiber response and synchrony in multiple functional components.
    1. Computational and Systems Biology

    A transfer-learning approach to predict antigen immunogenicity and T-cell receptor specificity

    Barbara Bravi, Andrea Di Gioacchino ... Rémi Monasson
    An interpretable machine learning approach can recapitulate the molecular features associated to immune protein-protein binding and leverage them for the prediction of immune response specificity.
    1. Computational and Systems Biology
    2. Ecology

    Gut Health: The value of connections

    Vanessa Rossetto Marcelino
    High proportions of gut bacteria that produce their own food can be an indicator for poor gut health.
    Insight
    Formats available:
    • HTML
    • PDF
    1. Computational and Systems Biology

    A hierarchical model for external electrical control of an insect, accounting for inter-individual variation of muscle force properties

    Dai Owaki, Volker Dürr, Josef Schmitz
    A near-linear relationship between electrical stimulus duration and resultant joint torque in stick insects has been unveiled, enhancing control strategies in biohybrid robotics.
    1. Cancer Biology
    2. Computational and Systems Biology

    Spatial transformation of multi-omics data unlocks novel insights into cancer biology

    Mateo Sokač, Asbjørn Kjær ... Nicolai J Birkbak
    GENIUS provides a deep learning framework for multi-omics integration that transforms data into spatial images, using integrated gradients to reveal novel and critical cancer gene association.
    1. Computational and Systems Biology
    2. Neuroscience

    Adult-born granule cells improve stimulus encoding and discrimination in the dentate gyrus

    Diego M Arribas, Antonia Marin-Burgin, Luis G Morelli
    Heterogeneity in the population of granule cells in the dentate gyrus, which includes immature and mature neurons with distinct intrinsic properties, contributes to the population's enhanced encoding capabilities and ability to discriminate correlated stimuli.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Dynamic allosteric networks drive adenosine A1 receptor activation and G-protein coupling

    Miguel A Maria-Solano, Sun Choi
    Deciphering the dynamics of the allosteric communication and the formation of transient pockets along the activation pathway of G-protein-coupled receptors provides useful information for the design of allosteric modulators.