Browse our latest Developmental Biology articles

Page 117 of 211
    1. Cell Biology
    2. Developmental Biology

    Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

    Chih-Yung S Lee, Andrea Putnam ... Geraldine Seydoux
    The intrinsically-disordered protein MEG-3 recruits mRNAs to P granules by forming gel-like condensates with ribosome-depleted mRNAs.
    1. Neuroscience
    2. Developmental Biology

    Phrenic-specific transcriptional programs shape respiratory motor output

    Alicia N Vagnozzi, Kiran Garg ... Polyxeni Philippidou
    Molecular programs regulated by Hox5 transcription factors establish a set of inhibitory inputs onto phrenic motor neurons that control the pattern of respiratory motor output.
    1. Developmental Biology
    2. Plant Biology

    Plant Reproduction: Shaping the genome of plants

    Ajeet Chaudhary, Rachele Tofanelli, Kay Schneitz
    Fertilization of an egg cell by more than one sperm cell can produce viable progeny in a flowering plant.
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    1. Developmental Biology
    2. Plant Biology

    Selective egg cell polyspermy bypasses the triploid block

    Yanbo Mao, Alexander Gabel ... Rita Groß-Hardt
    A ménàge à trois introduces extra DNA only to plant embryos, thus skipping endosperm-induced seed hybridization barriers.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

    Hessel Honkoop, Dennis EM de Bakker ... Jeroen Bakkers
    Single-cell RNA sequencing reveals Nrg1/ErbB2-induced metabolic reprogramming as a pivotal event for cardiomyocyte proliferation during heart regeneration.
    1. Cell Biology
    2. Developmental Biology

    Metabolic modulation regulates cardiac wall morphogenesis in zebrafish

    Ryuichi Fukuda, Alla Aharonov ... Didier YR Stainier
    3D single cell imaging and genetic analyses reveal a new role of cardiac metabolism in cardiac wall morphogenesis.
    1. Developmental Biology

    Heart Development and Regeneration: Metabolism makes and mends the heart

    Megan L Martik
    Experiments in zebrafish have shed new light on the relationship between development and regeneration in the heart.
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    1. Developmental Biology
    2. Immunology and Inflammation

    Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila

    Katrin Kierdorf, Fabian Hersperger ... Marc S Dionne
    A cytokine partly derived from macrophages is required to promote normal muscle health and metabolism by inhibiting the activity of the insulin signalling pathway in the fruitfly Drosophila melanogaster.
    1. Cell Biology
    2. Developmental Biology

    The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer

    Ling-Shih Chang, Minseong Kim ... Christof Niehrs
    Two cancer related proteins, tyrosine phosphatase PTPRK and ubiquitin ligase ZNRF3, interact to downregulate Wnt receptors, thereby regulating Spemann organizer function during Xenopus development.
    1. Developmental Biology
    2. Immunology and Inflammation

    Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice

    Ken-ichi Hirano, Akiko Suganami ... Katsuto Hozumi
    Notch ligand, Dll4 needs the flexible loop structure in the MNNL domain of the extracellular region to efficiently trigger the Notch signaling.