Browse our latest Developmental Biology articles

Page 132 of 211
    1. Developmental Biology

    3D Imaging: Taking a closer look at whole organisms

    Noriko Ichino, Stephen C Ekker
    By enabling researchers to image whole zebrafish with cellular resolution, X-ray histotomography will improve our understanding of the biological differences between individuals of the same species.
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    1. Developmental Biology
    2. Neuroscience

    FOXP2 exhibits projection neuron class specific expression, but is not required for multiple aspects of cortical histogenesis

    Ryan J Kast, Alexandra L Lanjewar ... Pat Levitt
    Foxp2 is dispensable for several features of cortical development that were previously considered to depend on its function.
    1. Developmental Biology
    2. Neuroscience

    A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

    Meenakshi Prajapati-DiNubila, Ana Benito-Gonzalez ... Angelika Doetzlhofer
    Opposing gradients of activin A and follistatin within the spiral shaped mammalian cochlea instruct the graded pattern of mechano-sensory hair cell formation.
    1. Developmental Biology

    Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography

    Yifu Ding, Daniel J Vanselow ... Keith C Cheng
    X-ray histotomography produces the first 3-dimensional images with the combined submicron resolution, centimeter fields-of-view, soft-tissue contrast, and potential throughput to enable quantitative, histopathological and centimeter-scale phenotyping for whole-organism phenomics.
    1. Developmental Biology

    Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF

    Manju Sharma, Anuj Srivastava ... Robert E Braun
    Promyelocytic leukemia zinc finger (PLZF) regulates the proliferative rate of eomesodermin (EOMES) spermatogonial stem cells.
    1. Developmental Biology

    Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation

    Helen Strutt, Jessica Gamage, David Strutt
    Casein kinase Iε phosphorylation has opposite effects on the stability of the core planar polarity proteins Strabismus and Dishevelled, leading to their sorting to opposite cell ends.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stem cell topography splits growth and homeostatic functions in the fish gill

    Julian Stolper, Elizabeth Mayela Ambrosio ... Lazaro Centanin
    The fish gill, an ever-growing organ with fast turnover rate, displays dedicated stem-cell populations for growth and homeostasis that are interchangeable upon external challenges.
    1. Cell Biology
    2. Developmental Biology

    Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle

    Chet Huan Oon, Kenneth E Prehoda
    Neural stem cells dynamically polarize through the stepwise activity of polarized cortical targeting and cortical flows that coalescence discontinuous cortical patches into an organized cap structure.
    1. Developmental Biology

    Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

    Lin Grimm, Hiroyuki Nakajima ... Benjamin M Hogan
    Genetic studies reveal a role for Yap1 in lymphatic endothelial progenitor cell sprouting and proliferation during early zebrafish lymphatic vascular development.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction

    Mohsen Afshar Bakooshli, Ethan S Lippmann ... Penney M Gilbert
    Human skeletal muscle progenitors and motor neurons self-organize in three-dimensional co-culture to form functional neuromuscular junctions that developmentally mature from the embryonic to the adult state.