Browse our latest Developmental Biology articles

NMNAT1, a ubiquitously expressed metabolic enzyme linked to inherited blinding disease, is crucial for the proper differentiation of photoreceptor cells and subsequent survival of multiple cell types in the retina.

Super-resolution imaging uncovers sparse occludin vs. clustered ZO1/claudin-5 architecture, and claudin-5 arrangement compacting during blood-brain-barrier tight-junction (TJ) maturation in which TJs become first restrictive to large and later to small molecules.

Differential binding kinetics of a master regulator to its target promoters can prevent spontaneous cell fate loss in a Caenorhabditis elegans neuron whose fate is controlled by a reversible switch.

Incremental deep learning enables accurate tracking of cell lineages in 3D with a modest investment in time and effort.

Signaling from the limb nerves regulates the rate of growth and the overall size of the regenerating limb.

Novel binding sites within a chordotonal-specific enhancer of the delilah gene integrates opposing signals of Prospero and D-Pax2 to control the alternative differentiation programs of cap versus scolopale cells.

Constitutive deficiency of AP2γ transcription factor impairs hippocampal glutamatergic neurogenesis and induces alterations on limbic-cortical connectivity that contribute to anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods.

The migrating pair of cardiac progenitors in the chordate Ciona robusta is the simplest possible supracellular cell collective whose organization helps them overcome resistance from surrounding embryonic tissues during cell migration.

Regrowing new body parts requires neural input to restore appropriately sized limbs in salamanders.

A combination of single-cell RNA sequencing of the developing septum and genetic fate mapping is used to analyze the origin of septal neurons.