Browse our latest Developmental Biology articles

Page 71 of 213
    1. Developmental Biology
    2. Neuroscience

    Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

    Dongjin R Lee, Christopher Rhodes ... Timothy J Petros
    Single-cell sequencing combined with in situ hybridizations reveal dynamic patterns of differentially expressed genes throughout the ventricular and subventricular zone of the embryonic mouse brain, which likely play important roles in cell fate determination.
    1. Developmental Biology
    2. Neuroscience

    Role of Nrp1 in controlling cortical inter-hemispheric circuits

    Fernando Martín-Fernández, Ana Bermejo-Santos ... Marta Nieto
    Transient expression of Nrp1 is required in postnatal stages for terminal arborization and innervation of secondary areas during the development of somatosensory callosal circuits.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants

    Richard J White, Eirinn Mackay ... Elisabeth M Busch-Nentwich
    Allele-specific gene expression can affect the results and interpretation of transcriptomic analyses in zebrafish mutants and has broader implications for work in other outbred organisms.
    1. Developmental Biology
    2. Physics of Living Systems

    Tissue Organization: When cells get in the flow

    Giovanna M Collu, Marek Mlodzik
    New imaging approaches question a long-standing model for how the eyes of fruit flies acquire their geometric patterning.
    Version of Record
    Insight
    1. Cell Biology
    2. Developmental Biology

    Pathway-specific effects of ADSL deficiency on neurodevelopment

    Ilaria Dutto, Julian Gerhards ... Travis H Stracker
    Analysis of adenylosuccinate lyase (ADSL) deficiency in multiple experimental systems reveals cell and organismal phenotypes and impaired neurodevelopment due to the attenuation of ADSL's roles in distinct pathways.
    1. Developmental Biology

    The Cl--channel TMEM16A is involved in the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks in mice

    Alena Maul, Antje Kathrin Huebner ... Christian A Hübner
    Ano1 deletion disrupts Ca2+ waves within Kölliker’s organ, reduces burst-firing activity and frequency selectivity of auditory brainstem neurons in the medial nucleus of the trapezoid body, and impairs the functional refinement of its projections to the lateral superior olive.
    1. Developmental Biology
    2. Physics of Living Systems

    Emergence of a geometric pattern of cell fates from tissue-scale mechanics in the Drosophila eye

    Kevin D Gallagher, Madhav Mani, Richard W Carthew
    Formation of a triangular lattice of photoreceptor clusters in the compound eye is driven by highly regulated cell flows in the eye epithelium, through a mechanochemical mechanism.
    1. Cell Biology
    2. Developmental Biology

    Somite morphogenesis is required for axial blood vessel formation during zebrafish embryogenesis

    Eric Paulissen, Nicholas J Palmisano ... Benjamin L Martin
    Retinoic acid-dependent somite morphogenesis induces notochord-endoderm separation required for midline angioblast migration and axial blood vessel development.
    1. Developmental Biology
    2. Neuroscience

    Slow oscillation–spindle coupling strength predicts real-life gross-motor learning in adolescents and adults

    Michael A Hahn, Kathrin Bothe ... Kerstin Hoedlmoser
    Individualized cross-frequency analyses reveal regionally specific slow oscillation–sleep spindle coupling precision as predictor for gross-motor learning dynamics.
    1. Cell Biology
    2. Developmental Biology

    The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth

    Shu Yang, Xuefeng Wu ... Xiaoyan Zheng
    The NDNF-like factor Nord is a Hedgehog-induced and extracellular-localized dosage-dependent BMP modulator that regulates Drosophila wing patterning and growth.