Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health

    Effects of side-effect risk framing strategies on COVID-19 vaccine intentions: a randomized controlled trial

    Nikkil Sudharsanan, Caterina Favaretti ... Alain Vandormael
    Small changes to the way COVID-19 vaccine side-effect rates are framed and communicated have meaningful impacts on individuals' vaccination intentions.
    1. Epidemiology and Global Health

    COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)

    Wan Yang, Jeffrey L Shaman
    Model-inference reconstructed SARS-CoV-2 transmission dynamics in South Africa during March 2020 to February 2022, and quantified the immune erosion potential and transmissibility of three major variants (Beta, Delta, and Omicron), highlighting their common characteristics and the need for more proactive preparedness.
    1. Epidemiology and Global Health

    Adiposity may confound the association between vitamin D and disease risk – a lifecourse Mendelian randomization study

    Tom G Richardson, Grace M Power, George Davey Smith
    Genetic analyses provide evidence that adiposity influences vitamin D levels at different timepoints over the lifecourse, suggesting that associations previously reported between vitamin D deficiency and disease by conventional epidemiological studies may have been prone to confounding.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Genomic epidemiology of the first two waves of SARS-CoV-2 in Canada

    Angela McLaughlin, Vincent Montoya ... Jeffrey B Joy
    Canadian COVID-19 travel restrictions imposed in March 2020 greatly reduced SARS-CoV-2 importations, but were insufficient to prevent new sublineages of similar transmissibility from being introduced and replacing early sublineages.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

    Fei Chen, Burcu F Darst ... Christopher A Haiman
    A previously developed multi-ancestry polygenic risk score is potentially an effective prostate cancer risk stratification tool across ancestry populations.
    1. Epidemiology and Global Health

    Population-based sequencing of Mycobacterium tuberculosis reveals how current population dynamics are shaped by past epidemics

    Irving Cancino-Muñoz, Mariana G López ... Iñaki Comas
    Low-burden does not mean low local transmission, and tailor-made strategies are needed to control TB based on the knowledge of the local transmission dynamics.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study

    Charles N Agoti, Lynette Isabella Ochola-Oyier ... George Githinji
    Genomic analysis of initial SARS-CoV-2 waves in Kenya revealed Mombasa City as a key gateway for variants entering Coastal Kenya with onward inter-county transmission highlighting significance of surveillance in major cities for early warning of lineages entering local populations.
    1. Ecology
    2. Epidemiology and Global Health

    Predictors of human-infective RNA virus discovery in the United States, China, and Africa, an ecological study

    Feifei Zhang, Margo Chase-Topping ... Mark EJ Woolhouse
    In three different regions including the United States, China, and Africa, virus discoveries were strongly associated with GDP and land use, but were less likely to be associated with climate and biodiversity variables than at a global scale.
    1. Epidemiology and Global Health

    Science Forum: Adding a One Health approach to a research framework for minority health and health disparities

    Brittany L Morgan, Mariana C Stern ... Laura Fejerman
    Adding a One Health approach to a research framework for minority health and health disparities encourages the exploration of new avenues of inquiry, multidisciplinary collaboration, and the consideration of new determinants of health.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The influence of biological, epidemiological, and treatment factors on the establishment and spread of drug-resistant Plasmodium falciparum

    Thiery Masserey, Tamsin Lee ... Melissa A Penny
    Models of malaria and treatment dynamics were combined with emulator-based global sensitivity analysis to elucidate the interplay between drug, biology, and epidemiological factors on the evolution of resistance to malaria treatments, including artemisinin.