Browse our latest Evolutionary Biology articles

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    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Protease Inhibitors: Developing evolution-resistant drugs for COVID-19

    Daniel M Weinreich
    Analyzing how mutations affect the main protease of SARS-CoV-2 may help researchers develop drugs that are effective against current and future variants of the virus.
    Version of Record
    Insight
    1. Cell Biology
    2. Evolutionary Biology

    Flagellar energy costs across the tree of life

    Paul E Schavemaker, Michael Lynch
    Prokaryotic and eukaryotic flagella follow a common trend in swimming cost-effectiveness, but eukaryotic flagella are too large for cells with prokaryote volumes, yielding insight into flagellar dissimilarity between taxa.
    1. Developmental Biology
    2. Evolutionary Biology

    Lung evolution in vertebrates and the water-to-land transition

    Camila Cupello, Tatsuya Hirasawa ... Paulo M Brito
    The primitive state of vertebrate lungs is unpaired, evolving to be truly paired in the lineage towards the tetrapods, increasing the pulmonary efficiency during the water-to-land transition.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice

    Shauni Doms, Hanna Fokt ... John F Baines
    Genetic variation influencing the gut microbiome is abundant among incipient mammalian host species, and cospeciating bacterial taxa display a unique genetic architecture.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The spatiotemporal patterns of major human admixture events during the European Holocene

    Manjusha Chintalapati, Nick Patterson, Priya Moorjani
    Development of a genomic dating method that leverages ancestry covariance patterns in a single diploid individual reveals the timing of major admixture events during the European Holocene.
    1. Evolutionary Biology

    Fitness consequences of outgroup conflict

    Ines Braga Goncalves, Amy Morris-Drake ... Andrew N Radford
    A detailed discussion of the broad range of immediate, delayed, cumulative, and third-party fitness consequences arising from outgroup conflict showcases the importance of this neglected aspect of sociality as a powerful and widespread evolutionary force.
    1. Developmental Biology
    2. Evolutionary Biology

    Gene expression phylogenies and ancestral transcriptome reconstruction resolves major transitions in the origins of pregnancy

    Katelyn Mika, Camilla M Whittington ... Vincent J Lynch
    Mammals evolved an invasive placenta early in the origins of pregnancy.
    1. Evolutionary Biology

    Morphometric analysis of lungfish endocasts elucidates early dipnoan palaeoneurological evolution

    Alice M Clement, Tom J Challands ... John A Long
    Cranial endocasts of fossil and extant lungfish, analysed via tomography and novel principle component analyses designed for use with missing data, show that lungfish forebrain and inner ear regions show the most variation in brain shape evolution through time.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals

    Stéphane Peyrégne, Janet Kelso ... Svante Pääbo
    Analyses of spindle genes with missense changes in modern humans reveal evidence for positive selection since the split with archaic humans and show that modern humans interacted with Neandertals more than once in the past 200,000 years.
    1. Ecology
    2. Evolutionary Biology

    Host-parasite coevolution promotes innovation through deformations in fitness landscapes

    Animesh Gupta, Luis Zaman ... Justin R Meyer
    An interdisciplinary approach combining high throughput genotype-to-phenotype mapping, population genetic simulations, and experimental evolution provides an answer to the question of how populations evolve new functions by providing tests of the role antagonistic coevolution plays in pressuring populations to innovate.