The protein components of an essential and conserved meiotic interface, the synaptonemal complex, have highly conserved coil-coiled domains and protein length, despite highly diverged sequence.
Arielle Woznica, Ashwani Kumar ... Julie K Pfeiffer
Developing Monosiga brevicollis as a model to study choanoflagellate immune responses reveals that the innate immune protein STING mediates responses to cyclic dinucleotides in choanoflagellates, providing insight into the evolution of STING signaling on the animal stem lineage.
Lucia L Prieto-Godino, Hayden R Schmidt, Richard Benton
A 'hotspot' position in an olfactory receptor protein family underlies changes in odor tuning in different receptors at different times during evolution.
Christopher W Bakerlee, Angela M Phillips ... Michael M Desai
Experimentally evolved budding yeast populations reveal the role of contingency and chance in shaping the emergence and dynamics of pleiotropic effects of adaptation.
Nicholas O Burton, Alexandra Willis ... Eric A Miska
Intergenerational adaptations to stress play a critical role in organismal responses to changing environments and are largely lost or erased after one generation.
Jennifer E Jones, Valerie Le Sage ... Seema S Lakdawala
Phylogenetic relationships between viral RNA segments are distinct between subtypes and lineages of seasonal human influenza A viruses and implicate RNA-RNA relationships as novel drivers of influenza virus evolution.