Lucia L Prieto-Godino, Hayden R Schmidt, Richard Benton
A 'hotspot' position in an olfactory receptor protein family underlies changes in odor tuning in different receptors at different times during evolution.
Christopher W Bakerlee, Angela M Phillips ... Michael M Desai
Experimentally evolved budding yeast populations reveal the role of contingency and chance in shaping the emergence and dynamics of pleiotropic effects of adaptation.
Nicholas O Burton, Alexandra Willis ... Eric A Miska
Intergenerational adaptations to stress play a critical role in organismal responses to changing environments and are largely lost or erased after one generation.
Jennifer E Jones, Valerie Le Sage ... Seema S Lakdawala
Phylogenetic relationships between viral RNA segments are distinct between subtypes and lineages of seasonal human influenza A viruses and implicate RNA-RNA relationships as novel drivers of influenza virus evolution.
Gabriela Santos-Rodriguez, Irina Voineagu, Robert J Weatheritt
An analysis of the genomic features that distinguish conserved from species-specific circular RNAs reveals that the expansion of the downstream intron by insertion of retrotransposons stabilizes circular RNAs' production across 30+ millions years of evolution.
Evolutionary analyses suggest that most mammalian circRNAs did not emerge from common ancestral circRNA precursors, arguing against widespread functional conservation.
Irreversible differentiation into somatic cells is evolutionarily optimal if changing cell phenotype is costly, a few somatic cells already improve the organism's performance, and the organism is large enough.