Browse our latest Genetics and Genomics articles

Membrane lipids are involved in the maturation and cytotoxicity of Parkinson's synphilin-1 inclusion bodies.

A method for genetically barcoding Drosophila is developed and used to tag defined cell populations in vivo for single-cell transcriptomics experiments and to enable multiplexed behavioral analysis.

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

Transport of double-stranded RNA from parental circulation to progeny using the transmembrane protein SID-1 can occur through multiple routes during C. elegans development and buffer heritable changes in gene expression.

Template switching during DNA replication is a frequent source of adaptive gene amplification.

Smad and Schnurri transcription factors engage in context-dependent interactions as well as independent genomic activities, leading to regulation of collagen secretion to mediate body size regulation in C. elegans.

Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.

Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m⁶A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.