Browse our latest Genetics and Genomics articles

Signaling through nicotinic acetylcholine receptors in enterocytes impacts barrier integrity in the Drosophila intestine by regulating formation of the peritrophic matrix.

The application of real-time genomics by long-read nanopore sequencing to environmental samples creates a new trajectory for non-invasive genomics-based monitoring of critically endangered wildlife.

Leveraging the X-LD method for estimating inter-chromosomal linkage disequilibrium in the human genome uncovers a universal extended LD pattern, consistent with observations in 1KG cohorts.

A long-term arousal state is linked to the acute decision to leave a food patch by sensory neurons that integrate neuromodulatory information, food intake, and environmental signals.

The hadal snailfish rapidly evolved and adapted to extreme deep-sea environments, modifying crucial genes and enhancing tolerance to high-hydrostatic pressure through ferritin gene duplication.

CFAP52 is a candidate for genetic diagnosing male infertility with defects of sperm head-tail connection and flagella development.

A randomized CRISPR-based gene silencing approach overcomes functional redundancy and discovers virulence-critical gene combinations in the pathogen Legionella pneumophila.

Pulsatile chromatin opening stimulated by naturally-occurring plasma growth hormone pulses is one of two GH-determined mechanisms that establish widespread sex differences in hepatic chromatin accessibility and epigenetic regulation, both closely linked to sex differences in liver gene transcription and function.

LRRC23 is a radial spoke 3 head component essential for normal sperm motility and fertility in mammals.

In this Special Issue we present a range of studies that showcase novel approaches that researchers are exploring to better decipher the link between genotype and phenotype.