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PSTPIP2 reduced IL-19 secretion by inhibiting activation of the NF-κB pathway in renal tubular epithelial cells (RTECs), reducing the generation of neutrophil extracellular trap, which can participate in both aristolochic acid I-induced renal injury and apoptosis in RTECs.

A microbiome metabolite alleviates liver steatosis and inflammation, and shows its potential as a therapeutic modality for non-alcoholic fatty liver disease.

Acute myocardial infarction patient-derived endothelial cells display a strong mitochondrial proton coupling with excess ROS production, enhanced glutamine metabolism and a carbon source switch from glucose to glutamine.

Metabolomic analyses have developed and validated serum androstenedione as a reliable and effective diagnostic and predictive biomarker for primary angle closure glaucoma in clinical routines.

Understanding the kinetics of dengue viruses in the bloodstream can provide insights into the clinical outcomes of the disease.

Development of a novel open-source device, 'E-Scope,' to simultaneously record electrophysiology and calcium imaging in freely behaving animals, discovering co-modulation of the cerebellum, and anterior cingulate cortex during social interaction.

A computer model predicts different mechanisms of blood pressure regulation and effective hypertensive therapy for males and females, thereby serving as a foundational tool for improved treatment precision.

Fibro-adipogenic progenitors in skeletal muscle contribute to the neuromuscular pathogenesis of spinal muscular atrophy, and depletion of SMN in chondrocytes reduces local IGF sigaling in growth plate.

A full radical curative dose of primaquine can be given to fully glucose-6-phosphate dehydrogenase-deficient males safely using an ascending dose regimen.

Vitamin A formation from β-carotene promotes an anti-inflammatory environment and remodeling of atherosclerotic lesions during the healing of atherosclerosis.