Browse our latest Medicine articles

Page 17 of 61
    1. Medicine

    SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury

    Xiaoyan Yang, Hsiang-Chun Chang ... Hossein Ardehali
    SIRT2 has detrimental effects in the heart and plays a role in cardiac response to injury and the progression of cardiac hypertrophy, and targeting SIRT2 may provide a novel avenue for the treatment of cardiac hypertrophy and ischemic disease.
    1. Medicine

    Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity

    Chandramohan Chitraju, Alexander W Fischer ... Robert V Farese Jr
    Inhibiting triglyceride storage in adipose tissue prevents obesity and improves metabolic health.
    1. Medicine

    Structural insights into the career path between pre- and postgraduate physician-scientist training programs

    Christopher S Williams, Emily J Gallagher ... Kyu Y Rhee
    Essential advice for trainees when evaluating postgraduate physician scientist training programs.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

    Thiruma V Arumugam, Asfa Alli-Shaik ... Jayantha Gunaratne
    Intermittent fasting orchestrates molecular shifts, yielding cardiovascular improvements, revealing novel cardioprotective mechanisms, and suggesting innovative pharmacological strategies for cardiovascular disease prevention and treatment.
    1. Medicine

    An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo

    Luyang Cao, Lixiang Ma ... Jingsong Xu
    Neutrophils are the predominant phagocytes that clear dead liver cells under normal physiological conditions.
    1. Epidemiology and Global Health
    2. Medicine
    3. Cancer Biology

    Special Issue: The impact of the COVID-19 pandemic on cancer prevention, control, care and survivorship

    Edited by Eduardo Franco et al.
    Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.
    1. Medicine

    Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice

    Hong Zheng, Qianjin Li ... Cheng-Kui Qu
    The balanced utilization of energy sources, namely carbohydrates and fats, by mitochondria, is critically important for the long-term maintenance of both skeletal muscle and heart health.
    1. Epidemiology and Global Health
    2. Medicine

    Development and validation of COEWS (COVID-19 Early Warning Score) for hospitalized COVID-19 with laboratory features: A multicontinental retrospective study

    Riku Klén, Ivan A Huespe ... David Gómez-Varela
    The new early warning system, COEWS, will improve the early identification and management of high-risk COVID-19 patients compared to the widely used NEWS2 by using easy-to-obtain clinical parameters that have been externally validated in a diverse multicontinental cohort of patients.
    1. Medicine

    Gender differences in submission behavior exacerbate publication disparities in elite journals

    Isabel Basson, Chaoqun Ni ... Vincent Larivière
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Epidemiology and Global Health
    2. Medicine

    Examining the perceived impact of the COVID-19 pandemic on cervical cancer screening practices among clinicians practicing in Federally Qualified Health Centers: A mixed methods study

    Lindsay Fuzzell, Paige Lake ... Rebecca Perkins
    In late 2021 and early 2022, many clinicians in Federally Qualified Health Centers (FQHCs) reported reduced cervical cancer screening and reported that pandemic-related staffing shortages impacted screening and follow-up.