Browse our latest Medicine articles

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    1. Epidemiology and Global Health
    2. Medicine

    Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

    Ewan Cameron, Alyssa J Young ... Katherine E Battle
    A demonstration of the power of routine case data and statistical modelling to guide the allocation of anti-malarial interventions in a resource-constrained setting.
    1. Medicine
    2. Neuroscience

    Recovery of consciousness and cognition after general anesthesia in humans

    George A Mashour, Ben JA Palanca ... Max B Kelz
    Cognitive reconstitution after pharmacologic unconsciousness is an extended process, executive function is more robust than expected, and the healthy human brain is resilient to the effects of deep general anesthesia.
    1. Genetics and Genomics
    2. Medicine

    A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease

    Qingyuan Zhao, Jingshu Wang ... Daniel J Rader
    High-density lipoprotein (HDL) subfraction traits appear to have heterogeneous effects on coronary artery disease, giving support to the HDL function hypothesis.
    1. Medicine

    Development and validation of a nomogram to better predict hypertension based on a 10-year retrospective cohort study in China

    Xinna Deng, Huiqing Hou ... Haijiang Wu
    A developed and validated nomogram better predicts the risk of hypertension based on a 10-year retrospective cohort study in China.
    1. Medicine

    Equity, Diversity and Inclusion: Introducing the MAVEN Leadership Training Initiative to diversify the scientific workforce

    Y Claire Wang, Elizabeth Brondolo ... The MAVEN Leadership Team
    The MAVEN Initiative has been designed to encourage mid-career women scientists, particularly women of color, to move into leadership positions in science.
    1. Computational and Systems Biology
    2. Medicine

    Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate

    Savannah F Bifulco, Griffin D Scott ... Patrick M Boyle
    In models reconstructed from MRI scans of patients with embolic stroke of undetermined source, computational simulations reveal that fibrosis has the intrinsic capacity to sustain arrhythmia drivers when subjected to triggered activity known to exist in patients with atrial fibrillation.
    1. Immunology and Inflammation
    2. Medicine

    Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

    Juana Serrano-Lopez, Shailaja Hegde ... Jose A Cancelas
    Endotoxemia recruits fast-acting anti-inflammatory innate myeloid progenitors from bone marrow into regional lymphatics through release of pre-formed Ccl19 secondary to NF-κB-independent, Traf6/IκB kinase-dependent signaling.
    1. Epidemiology and Global Health
    2. Medicine

    Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: A controlled before-and-after trial

    Jackie Knee, Trent Sumner ... Joe Brown
    Onsite sanitation maybe insufficient to interrupt transmission of enteric infections in high-burden urban settings, though risk of some infections may be reduced among children protected from birth.
    1. Medicine

    Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

    Salwa Naushin, Viren Sardana ... Shantanu Sengupta
    Widespread asymptomatic SARS-CoV2 infection affected nearly 100 million Indians by September 2020 with a subsequent decline in new cases, which may be attributable to increased population immunity, albeit seeing reduced neutralization activity at 6 months this respite may be temporary.
    1. Medicine

    Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

    Andrea Milzi, Enrico Domenico Lemma ... Mathias Burgmaier
    Assessing plaque biomechanics by optical coherence tomography highlights the importance of the disrupting effects of plaque stress, bringing stress concentrations as the prime movers of plaque rupture back into clinical practice.