Browse our latest Microbiology and Infectious Disease articles

Page 103 of 167
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete

    Kimberley H Gibson, Felipe Trajtenberg ... Charles Vaughn Sindelar
    The corkscrew-like motility of Spirochete bacteria is enabled by a unique, asymmetrically constructed flagellum that wraps around the cell body within the periplasm.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Adjusting for age improves identification of gut microbiome alterations in multiple diseases

    Tarini S Ghosh, Mrinmoy Das ... Paul W O'Toole
    A multi-cohort analysis of 2,500 gut microbiomes and five major diseases discovers that disease-microbiome associations display specific age-centric trends, with diseases characterized by age-centric trends of species gain/loss.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein

    Andrew I Flyak, Stormy E Ruiz ... Pamela J Bjorkman
    The crystal structure of neutralizing antibody AR3X in complex with HCV E2 glycoprotein reveals unusual features of antibody recognition in which a conserved epitope is recognized by distinct antibody poses.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    ParB spreading on DNA requires cytidine triphosphate in vitro

    Adam SB Jalal, Ngat T Tran, Tung BK Le
    A biochemical reconstitution shows that the accumulation of Caulobacter crescentus ParB on DNA requires cytidine triphosphate and a closed DNA substrate in vitro.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages

    Jay Lubow, Maria C Virgilio ... Kathleen L Collins
    Interactions between HIV-1 Env and human mannose receptor enhance HIV entry but restrict viral egress and spread in the absence of Vpr.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Plasmodium-infected erythrocytes induce secretion of IGFBP7 to form type II rosettes and escape phagocytosis

    Wenn-Chyau Lee, Bruce Russell ... Laurent Renia
    Plasmodium parasites use host-derived factors to form more rosettes and hamper phagocytosis, representing a new escape mechanism for the malaria parasites.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes

    Samantha Ebersoll, Marta Bogacz ... R Luise Krauth-Siegel
    African trypanosomes have a trypanothione-based mitochondrial thiol redox metabolism.
    1. Microbiology and Infectious Disease

    Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

    Miri Shnayder, Aharon Nachshon ... Michal Schwartz
    Single-cell and bulk expression analyses reveal that HCMV latent infection drives cells towards a weaker immune-responsive state, which is important for its expression and reactivation.
    1. Ecology
    2. Microbiology and Infectious Disease

    Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin

    Maria Cristina Stroe, Tina Netzker ... Axel A Brakhage
    A silent gene cluster of the fungus Aspergillus fumigatus is activated by a bacterium and leads to the production of a novel spore germination inhibitor targeting the inducing bacterium.
    1. Microbiology and Infectious Disease

    Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages

    Jonathan M Budzik, Danielle L Swaney ... Jeffery S Cox
    Measurement of post-translational modifications in primary macrophages infected with Mtb revealed phosphorylation of TAX1BP1, an autophagy receptor that enables full maturation of the Mtb autophagosome.