Browse our latest Microbiology and Infectious Disease articles

Page 111 of 167
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Apicomplexan-like parasites are polyphyletic and widely but selectively dependent on cryptic plastid organelles

    Jan Janouškovec, Gita G Paskerova ... Timur G Simdyanov
    Apicomplexan-like parasites originated several times independently and many of them contain cryptic plastid organelles, which demonstrate that the parasites evolved from photosynthetic algae.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Dengue genetic divergence generates within-serotype antigenic variation, but serotypes dominate evolutionary dynamics

    Sidney M Bell, Leah Katzelnick, Trevor Bedford
    Each dengue serotype contains moderate antigenic diversity, and population immunity drives clade turnover in a hyperendemic population.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

    M Azim Ansari, Elihu Aranday-Cortes ... Vincent Pedergnana
    Interferon lambda 4, a protein part of the innate immune response, drives major amino acids selection in patients chronically infected with hepatitis C virus.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Host-Pathogen Interactions: What makes the hepatitis C virus evolve?

    Thomas R O'Brien, Rune Hartmann, Ludmila Prokunina-Olsson
    Polymorphisms in the IFNL4 gene that affect both the form and the activity of the coded protein are associated with changes in the hepatitis C virus.
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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

    Nimisha Chaturvedi, Evguenia S Svarovskaia ... Jacques Fellay
    Integrated analysis of IFN-λ and HCV amino acid variation indicates the key role of host innate immunity in viral control.
    1. Ecology
    2. Microbiology and Infectious Disease

    Endangered wild salmon infected by newly discovered viruses

    Gideon J Mordecai, Kristina M Miller ... Curtis A Suttle
    Newly discovered viruses in dead and dying farmed Chinook salmon are widely distributed in threatened wild Chinook and sockeye salmon populations.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Pressure-driven release of viral genome into a host nucleus is a mechanism leading to herpes infection

    Alberto Brandariz-Nuñez, Ting Liu ... Alex Evilevitch
    Internal DNA pressure of tens of atmospheres inside a herpesvirus capsid powers ejection of the viral genome into a cell nucleus, causing infection.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin

    Juhye M Lee, Rachel Eguia ... Jesse D Bloom
    Single viral mutations can escape polyclonal human immunity to influenza hemagglutinin, but different mutations escape the immunity of different people.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Subtle selectivity in a pheromone sensor triumvirate desynchronizes competence and predation in a human gut commensal

    Johann Mignolet, Guillaume Cerckel ... Pascal Hols
    A new cell–cell communication system in Streptococcus salivarius, a human gut commensal, discriminates between close signaling molecules to specifically produce bacteriocin-based antimicrobials and disconnects it from foreign DNA acquisition.
    1. Microbiology and Infectious Disease

    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication

    Ting Pan, Zheng Song ... Hui Zhang
    USP49 can increase A3G protein expression and enhance its anti-HIV-1 activity, which is also correlated with hypermutations and affects the HIV-1 latent reservoir.