Browse our latest Microbiology and Infectious Disease articles

Page 119 of 167
    1. Microbiology and Infectious Disease

    The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane

    Cassandra Kamischke, Junping Fan ... Samuel I Miller
    An Acinetobacter baumannii ABC transporter likely facilitates transport of glycerophospholipids from the inner to the outer membrane.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Listeria monocytogenes cell-to-cell spread in epithelia is heterogeneous and dominated by rare pioneer bacteria

    Fabian E Ortega, Elena F Koslover, Julie A Theriot
    The pathogenic bacterium Listeria monocytogenes spreads infection using a two-tiered strategy, where most bacteria spread locally but a few 'pioneers' move further, increasing the likelihood of a persistent infection.
    1. Microbiology and Infectious Disease

    Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis

    Aleksandra Agapova, Agnese Serafini ... Luiz Pedro Sório de Carvalho
    Metabolomics and stable isotope labelling studies of virulent Mycobacterium tuberculosis reveal a de-centralised metabolic network able to utilise various amino acids as nitrogen sources to a better extent than ammonium.
    1. Microbiology and Infectious Disease

    TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb

    Xiancai Ma, Tao Yang ... Hui Zhang
    TRIM28 was found to be a versatile dual-function latency contributor by bridging both suppressive epigenetic modifications and RNAP II transcriptional-pausing, and can be a novel target to develop latency-reversing agents.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reprogramming the antigen specificity of B cells using genome-editing technologies

    James E Voss, Alicia Gonzalez-Martin ... Dennis R Burton
    Antibody paratopes can be added to the human repertoire by CRISPR-Cas9 editing of B lymphocytes using a strategy that allows for hypermutation and class switching of resulting B cell receptors.
    1. Microbiology and Infectious Disease

    Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

    Wannaporn Ittiprasert, Victoria H Mann ... Paul J Brindley
    Gene knock-out of the omega-1 ribonuclease of Schistosoma mansoni eggs resulted in immunologically impaired phenotype, showcasing the novel application of CRISPR/Cas9 genome editing and utility for functional genomics in schistosomes.
    1. Microbiology and Infectious Disease

    Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity

    Patpicha Arunsan, Wannaporn Ittiprasert ... Thewarach Laha
    Gene knockout of liver fluke granulin by CRISPR/Cas9 attenuates the virulence of infection with a carcinogenic liver fluke.
    1. Microbiology and Infectious Disease

    Tropical Diseases: Can CRISPR help in the fight against parasitic worms?

    Paul McVeigh, Aaron G Maule
    The first reports of CRISPR/Cas9 genome editing in flatworms could usher in a new era of research on these dangerous human parasites.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Meta-Research: Gender inequalities among authors who contributed equally

    Nichole A Broderick, Arturo Casadevall
    An analysis of papers in which two or more authors shared first-author position found that male authors were more likely than female authors to appear first in the author list.
    1. Microbiology and Infectious Disease

    Quorum sensing controls Vibrio cholerae multicellular aggregate formation

    Matthew Jemielita, Ned S Wingreen, Bonnie L Bassler
    A quorum-sensing-controlled program of multicellularity, aggregation, is identified in Vibrio cholerae, which may be important for transitions between the marine niche and the human host.