Browse our latest Microbiology and Infectious Disease articles

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    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Heterogeneous absorption of antimicrobial peptide LL37 in Escherichia coli cells enhances population survivability

    Mehdi Snoussi, John Paul Talledo ... Sattar Taheri-Araghi
    A rapid absorption and retention of antimicrobial peptides by dead Escherichia coli cells can increase the survivability of the cell population in a "cooperative" fashion.
    1. Microbiology and Infectious Disease

    Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells

    Siyuan Ding, Shu Zhu ... Harry B Greenberg
    Rotavirus infection induces phosphorylation and proteasomal degradation of MAVS to suppress host antiviral interferon signaling.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages

    Bridgette M Cumming, Kelvin W Addicott ... Adrie JC Steyn
    Quantifiable bioenergetic parameters, determined from extracellular flux analyses, are distinct between macrophages infected with Mycobacteriumtuberculosis or vaccine strain M. bovis BCG, enabling assessment of future vaccine and drug efficacy.
    1. Microbiology and Infectious Disease

    A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV

    Molly OhAinle, Louisa Helms ... Michael Emerman
    Host restriction factors that block cross-species transmission also play a role in limiting the replication of highly-adapted HIV-1 in IFN-stimulated cells.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

    Ruben Soto-Acosta, Xuping Xie ... Shelton Bradrick
    The Zika virus subgenomic flaviviral RNA binds to and inhibits the fragile X mental retardation protein, a novel Zika virus restriction factor.
    1. Microbiology and Infectious Disease

    Host genetic selection for cold tolerance shapes microbiome composition and modulates its response to temperature

    Fotini Kokou, Goor Sasson ... Itzhak Mizrahi
    Microbiome and transcriptomic profiling of genetically selected tropical fish with high and low tolerance to cold exposure revealed host control over microbiome composition and response to temperature changes.
    1. Microbiology and Infectious Disease

    High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types

    Landry Blanc, Isaac B Daudelin ... Véronique Dartois
    Penetration of the fluoroquinolones in tuberculosis lesions is heterogeneous even in fully cellular areas, is driven by macrophage content and decreases as the distance from lesion outer rim increases.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A Phytophthora effector recruits a host cytoplasmic transacetylase into nuclear speckles to enhance plant susceptibility

    Haiyang Li, Haonan Wang ... Yuanchao Wang
    PsAvh52 modulates epigenetic modification to enhance the susceptibility of soybean to Phytophthora sojae infection.
    1. Ecology
    2. Microbiology and Infectious Disease

    Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures

    Mauricio Seguel, Felipe Montalva ... Nicole Gottdenker
    In years with colder ocean temperatures, fur seal pups receive more maternal care and have a better energy balance, clearing hookworm infection earlier, which increases their chances of survival.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Plasmodium-specific atypical memory B cells are short-lived activated B cells

    Damián Pérez-Mazliah, Peter J Gardner ... Jean Langhorne
    Plasmodium-specific atypical memory B cells generated to naturally (mosquito) transmitted rodent malaria infection are short-lived activated B cells, and do not prevent resolution of infection or generation of long-lived memory.