Browse our latest Microbiology and Infectious Disease articles

Page 143 of 177
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance

    Robert M Cooper, Lev Tsimring, Jeff Hasty
    Killing their neighbors allows bacteria to steal genes, including antibiotic resistance genes, which we observed under a microscope, quantified, modeled, and predicted potentially guiding strategies to combat it.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Horizontal gene transfer: Learning from losers

    Benjamin Kirkup
    Bacteria can overcome environmental challenges by killing nearby bacteria and incorporating their DNA.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites

    Fabien Sindikubwabo, Shuai Ding ... Mohamed-ali Hakimi
    A versatile acetylation-methylation switch at lysine 31 on the lateral surface of histone H4 contributes to chromatin structure in apicomplexan parasites.
    1. Microbiology and Infectious Disease

    Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators

    Jutta Nesper, Isabelle Hug ... Urs Jenal
    Precise control of the bacterial flagellar motor determines bacterial cell dispersal and bacteria-surface interactions.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CpG and UpA dinucleotides in both coding and non-coding regions of echovirus 7 inhibit replication initiation post-entry

    Jelke Jan Fros, Isabelle Dietrich ... Peter Simmonds
    RNA virus replication is attenuated by an intrinsic restriction mechanism after introducing CpG/UpA dinucleotides into both non-translated and coding regions of viral genomes, which may be exploited in the design of attenuated virus vaccines.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis

    Teja Turk, Nadine Bachmann ... Swiss HIV Cohort Study
    A method to assess the risk of self-sustained HIV transmission in heterosexuals from phylogenetic and epidemiological data is developed and, when applied to the Swiss HIV epidemic, shows that this risk is negligibly small for Switzerland.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Competing scaffolding proteins determine capsid size during mobilization of Staphylococcus aureus pathogenicity islands

    Altaira D Dearborn, Erin A Wall ... Terje Dokland
    Cryo-electron microscopy and genetics show how Staphylococcus aureus pathogenicity island 1 hijacks the assembly pathway of a helper phage for its own propagation.
    1. Microbiology and Infectious Disease

    A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency

    Manabu Aoki, Hironori Hayashi ... Hiroaki Mitsuya
    GRL-142 is an HIV protease inhibitor with a unique structure and atto-to-picomolar potency against a wide range of HIV strains.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Epidemiological and ecological determinants of Zika virus transmission in an urban setting

    José Lourenço, Maricelia Maia de Lima ... Mario Recker
    An ento-epidemiological model reveals that what made the Zika virus a public health problem in Feira de Santana, Brazil, was a surprisingly high attack rate coupled with a low risk of Microcephaly per challenged pregnancy.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha

    Hiromi Maekawa, Annett Neuner ... Yoshinobu Kaneko
    Cdc5-dependent SPB regulation is linked to delayed cytoplasmic microtubule organization in Ogataea polymorpha.