The thickness of the periplasmic region is reduced in strains of pneumococcus that are deleted in genes responsible for the incorporation of teichoic acid in the cell envelope.
HSV-ΔICP34.5 reactivates latent HIV by modulating PP1-HSF1 and NF-κB pathways, offering a potential HSV-vectored therapeutic vaccine for a functional cure.
Aleksandra Prochera, Anoohya N Muppirala ... Meenakshi Rao
Genetic depletion of enteric glia in vivo disrupts antimicrobial peptide secretion by Paneth cells to change fecal microbial composition but does not broadly alter other intestinal programs.
Carley N Gray, Manickam Ashokkumar ... Michael Emerman
A block to more potent and specific release of HIV from latency has been identified as a subunit of the Integrator complex, which may aid strategies for HIV cure.
The novel divisome complex of Chlamydia trachomatis contains elements of the divisome and elongasome from other bacteria, and it requires the chromosomal translocase, FtsK, for its assembly.