Browse our latest Microbiology and Infectious Disease articles

Page 15 of 178
    1. Microbiology and Infectious Disease

    The capsule and genetic background, rather than specific individual loci, strongly influence in vitro pneumococcal growth kinetics

    Chrispin Chaguza, Daan W Arends ... Amelieke JH Cremers
    The pneumococcal capsular serotype and genetic background, as well as a combination of genomic loci, influence intrinsic pneumococcal growth kinetics, which may have implications for pneumococcal disease pathogenesis.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during Shigella infection

    Ana Teresa López-Jiménez, Dominik Brokatzky ... Serge Mostowy
    High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

    Shivraj M Yabaji, Vadim Zhernovkov ... Igor Kramnik
    Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.
    1. Microbiology and Infectious Disease
    2. Ecology

    BuzzWatch: Uncovering Multi-scale Temporal Patterns in Mosquito Behavior Through Continuous Long-term Monitoring

    Théo Maire, Zhong Wan ... Felix JH Hol
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

    Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Non-cognate immunity proteins provide broader defenses against interbacterial effectors in microbial communities

    Abigail Knecht, Denise Sirias ... Karine A Gibbs
    A biochemical and bioinformatics approach shows how T6SS immunity proteins bind to and neutralize a range of non-cognate effectors, which is critical for promoting bacterial fitness in mixed-strain environments.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites

    Steven P Maher, Malina A Bakowski ... Dennis E Kyle
    Drug repurposing screens reveal several epigenetic inhibitors as active against P. vivax hypnozoites demonstrating that epigenetic pathways play a central role in hypnozoite quiescence.
    1. Microbiology and Infectious Disease

    The increase in cell volume and nuclear number of the koji-fungus Aspergillus oryzae contributes to its high enzyme productivity

    Ayaka Itani, Haruto Motomura ... Norio Takeshita
    More nuclei and cell volume, more enzymes in koji-fungus Aspergillus oryzae.
    1. Microbiology and Infectious Disease

    A SHERLOCK toolbox for eco-epidemiological surveillance of African trypanosomes in domestic pigs from Western Africa

    Roger Eloiflin, Elena Pérez-Antón ... Brice Rotureau
    A novel array of CRISPR-based SHERLOCK tests for RNA detection was developed for eco-epidemiological surveillance of human and animal African trypanosomes from Western Africa with domestic pigs as sentinels.