Browse our latest Microbiology and Infectious Disease articles

Page 16 of 177
    1. Microbiology and Infectious Disease

    Multi-omics investigation of spontaneous T2DM macaque emphasizes gut microbiota could up-regulate the absorption of excess palmitic acid in the T2DM progression

    Xu Liu, Yuchen Xie ... Jing Li
    Gut dysbiosis and specific microbiota composition promoted the absorption of excess palmitic acid in the ileum, driving its accumulation in the serum.
    1. Microbiology and Infectious Disease

    Temporal dynamics of viral fitness and the adaptive immune response in HCV infection

    Melanie Rose Walker, Preston Leung ... Rowena A Bull
    Early immune pressure and co-occurring mutations drive changes in hepatitis C virus fitness and evolution, revealing key dynamics in the establishment of chronic infection.
    1. Microbiology and Infectious Disease

    A novel mechanism for bacterial sporulation based on programmed peptidoglycan degradation

    Carlos A Ramírez Carbó, Oihane Irazoki ... Beiyan Nan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Innate immunity and training to subvert original antigenic sin by the humoral immune response

    Faez Amokrane Nait Mohamed, Daniel Lingwood
    It is proposed that innate immune cells are positioned to activate the naïve B cell repertoire and rational application of training stimuli could enforce this, offsetting original antigenic sin, wherein recall of ‘off-target’ B cell memory can obscure vaccine effectiveness.
    1. Microbiology and Infectious Disease

    Multi-omics single-cell analysis reveals key regulators of HIV-1 persistence and aberrant host immune responses in early infection

    Dayeon Lee, Sin Young Choi ... Jihwan Park
    KLF2 activity and impaired interferon signaling contribute to HIV-1 persistence by restricting antiviral immunity in infected CD4 T cells during early infection.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Benchmarking and optimization of methods for the detection of identity-by-descent in high-recombining Plasmodium falciparum genomes

    Bing Guo, Shannon Takala-Harrison, Timothy D O'Connor
    hmmIBD outperforms alternative tools in detecting genome segments that are identical-by-descent and uncovering signals of positive selection and demographic history in malaria parasite genomes, underscoring the importance of tool prioritization and optimization for reliable malaria genomic surveillance.
    1. Microbiology and Infectious Disease

    The interplay of membrane tension and FtsZ filament condensation on the initiation and progression of cell division in B. subtilis

    Diego A Ramirez-Diaz, Lei Yin ... Ethan C Garner
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Navigating contradictions in enteric chemotactic stimuli

    Kailie Franco, Zealon Gentry-Lear ... Arden Baylink
    Motile Enterobacteriaceae override chemorepulsion from the microbiota metabolite indole in favor of nutrient attraction, challenging the idea that indole taxis protects the host against intestinal infection.
    1. Microbiology and Infectious Disease

    A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor

    Brenna Walton, Serena Abbodante ... Arne Rietsch
    Certain bacteriophage are specifically adapted to infecting biofilm bacteria by exploiting biofilm characteristics, such as the exopolysaccharides produced by bacteria in biofilms.
    1. Microbiology and Infectious Disease

    Lacticaseibacillus rhamnosus P118 enhances host tolerance to Salmonella infection by promoting microbe-derived indole metabolites

    Baikui Wang, Xianqi Peng ... Min Yue
    Probiotic P118 against Salmonella infections by directly antibacterial actions, inhibiting Salmonella colonization and invasion, attenuating macrophage pro-inflammatory responses, and modulating gut microbiota mediated by microbe-derived indole metabolites.