Browse our latest Microbiology and Infectious Disease articles

Page 54 of 173
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Science Forum: A low-cost, open-source evolutionary bioreactor and its educational use

    Vishhvaan Gopalakrishnan, Dena Crozier ... Jacob G Scott
    The EVolutionary biorEactor (EVE) can be built for less than $200, and can be used to evaluate microbial population dynamics in the lab and to teach evolution in high schools.
    1. Ecology
    2. Microbiology and Infectious Disease

    Variation in the ACE2 receptor has limited utility for SARS-CoV-2 host prediction

    Nardus Mollentze, Deborah Keen ... Daniel G Streicker
    The success of angiotensin-converting enzyme 2 (ACE2)-based predictions of severe acute respiratory syndrome-associated virus 2 (SARS-CoV-2) host range stems from phylogenetic correlation, allowing development of scalable models which predict susceptibility to SARS-CoV-2 and other sarbecoviruses without requiring additional ACE2 sequencing.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Acetylation of a fungal effector that translocates host PR1 facilitates virulence

    Jingtao Li, Xiaoying Ma ... Wenxing Liang
    Acetylation stabilizes a fungal effector to mis-localize a key defense protein, leading to compromised immunity of host plants.
    1. Microbiology and Infectious Disease

    An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria

    Kuldeepkumar R Gupta, Celena M Gwin ... E Hesper Rego
    Asymmetric growth in mycobacteria requires a protein that is involved in trafficking mycolic acids to the outer membrane.
    1. Microbiology and Infectious Disease

    T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus

    Matthew D Lauver, Ge Jin ... Aron E Lukacher
    Loss of T cell control during persistent polyomavirus infection, in the setting of a limited antiviral antibody response, facilitates emergence of antibody-escape viruses carrying the potential for neurovirulence.
    1. Microbiology and Infectious Disease

    Phage resistance profiling identifies new genes required for biogenesis and modification of the corynebacterial cell envelope

    Amelia C McKitterick, Thomas G Bernhardt
    Using bacteriophages as probes, new genes involved in cell surface construction were identified in a class of bacteria that includes important pathogens like Mycobacterium tuberculosis.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice

    Reem Abdel-Haq, Johannes CM Schlachetzki ... Sarkis K Mazmanian
    Microbiome-diet interactions shape microglia reactivity in a mouse model of Parkinson's disease.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    High-throughput imaging and quantitative analysis uncovers the nature of plasmid positioning by ParABS

    Robin Köhler, Eugen Kaganovitch, Seán M Murray
    The ParABS system positions plasmids precisely within the cell but just below the threshold for oscillatory dynamics.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL

    Donté Alexander Stevens, Christopher Beierschmitt ... Matthew D Daugherty
    Evolution-guided functional analyses identify an activating adaptor of the dynein intracellular transportation machinery, NINL, as a novel component of the antiviral immune response and reveal a mechanism by which viruses antagonize NINL function in a species-specific manner.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CD169+ macrophages orchestrate plasmacytoid dendritic cell arrest and retention for optimal priming in the bone marrow of malaria-infected mice

    Jamie Moore-Fried, Mahinder Paul ... Gregoire Lauvau
    CD169+ macrophages in the bone marrow of malaria-infected mice uptake infected red blood cells, and establish a functional interaction that is required to activate plasmacytoid dendritic cells to secrete type I interferon and leave the bone marrow.