Browse our latest Microbiology and Infectious Disease articles

Page 56 of 173
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolution: A life LINE for large viruses

    Eugene V Koonin, Mart Krupovic
    As long suspected, poxviruses capture host genes through a reverse-transcription process now shown to be mediated by retrotransposons.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    LINE-1 retrotransposons facilitate horizontal gene transfer into poxviruses

    M Julhasur Rahman, Sherry L Haller ... Stefan Rothenburg
    A new experimental system of horizontal gene transfer demonstrates that host retrotransposons facilitate the transfer of host genes into poxviruses.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Poxviruses capture host genes by LINE-1 retrotransposition

    Sarah M Fixsen, Kelsey R Cone ... Nels C Elde
    Active selfish genetic elements in infected cells aid virus adaptation by catalyzing the transfer of host genes to virus genomes.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors

    Hadar Cohen, Noam Baram ... Motti Gerlic
    A horizontally shared type VI secretion system affects the interaction between vibrios and eukaryotic hosts.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Group II truncated haemoglobin YjbI prevents reactive oxygen species-induced protein aggregation in Bacillus subtilis

    Takeshi Imai, Ryuta Tobe ... Hisaaki Mihara
    The repair of oxidatively damaged proteins by the newly discovered activity in YjbI is important for the adaptation of Bacillus subtilis to oxidative environments.
    1. Microbiology and Infectious Disease

    Hemocyte differentiation to the megacyte lineage enhances mosquito immunity against Plasmodium

    Ana Beatriz F Barletta, Banhisikha Saha ... Carolina Barillas-Mury
    Toll signaling modulates hemocyte differentiation into the megacyte lineage and their recruitment to the midgut greatly enhances mosquito immunity against Plasmodium.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients

    Bronner P Gonçalves, Matthew Hall ... ISARIC Clinical Characterisation Group
    Combined analyses of publicly available population-level variant data and detailed individual-level clinical data can be used to quantify the clinical impact of new SARS-CoV-2 variants in different settings.
    1. Microbiology and Infectious Disease

    c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis

    Nadine Vollmuth, Lisa Schlicker ... Thomas Rudel
    The central immune modulator interferon-gamma downregulates the proto-oncogene c-Myc to shut down host cell metabolism and interfere with infection of epithelial cells by obligate intracellular pathogenic Chlamydia trachomatis.
    1. Microbiology and Infectious Disease

    Distinct regions of H. pylori’s bactofilin CcmA regulate protein–protein interactions to control helical cell shape

    Sophie R Sichel, Benjamin P Bratton, Nina R Salama
    The helical cell shape of Helicobacter pylori depends on the polymerizing cytoskeletal protein CcmA’s recruitment to the cell envelope by Csd5 and CcmA’s indirect stabilization of a periplasmic cell wall hydrolase via interactions with the transmembrane protein Csd7.
    1. Microbiology and Infectious Disease

    The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis

    Anne Günther, Matthias Hose ... Wiebke Hansen
    Host cell acid ceramidase activity contributes to the regulation of erythrocyte maturation and thereby affects the frequency of target cells for rodent Plasmodium yoelii parasites.