Browse our latest Microbiology and Infectious Disease articles

Combining ribosome profiling and RNA sequencing illuminates novel features of porcine reproductive and respiratory syndrome virus gene expression, including the regulation of polyprotein stoichiometry through temporal modulation of ribosomal frameshifting and the synthesis of non-canonical transcripts.

A simple model provides an accessible framework to infer macroscopic parameters of effective resource competition from longitudinal studies of microbial communities.

The efficiency with which ribosomes shift reading frames when decoding viral RNA may change over the course of an infection.

A specific gut microbe Paracoccus aminovorans enhances host colonization of the human pathogen Vibrio cholerae by forming dual-species biofilm structures.

The crenarchaeon Sulfolobus synthesizes the N-glycan core in the identical way as all Eukaryotes, which strengthens the hypothesis that the eukaryotic N-glycosylation is acquired from an ancient archaeon during eukaryogenesis.

The use of liquid-infused catheters results in significant reduction of bladder and catheter colonization, systemic dissemination, and bladder inflammation in a clinically relevant mouse model of CAUTI by targeting host-protein deposition on the urinary catheter.

A replicating RNA vaccine platform generated significant immunity against SARS-CoV2 in mice and hamsters, and can be updated to target variants of concern.

Proteins for bacterial flagella biogenesis contain two discrete export signals, recognised sequentially by the flagellar Type III Secretion System to facilitate initial docking and subsequent opening of the export gate.

Noise-averaging cooperation (NAC) is a novel theory for the emergence of microbial cross-feeding by which noisy intracellular metabolism can promote cooperation and cross-feeding among cells.

Characterization of PML subnuclear structures during human cytomegalovirus infection demonstrates that prolonged interferon and DNA damage signaling can induce giant PML nuclear bodies which sequentially entrap both nucleic acids and viral proteins as a cytoprotective mechanism.