Browse our latest Microbiology and Infectious Disease articles

High-throughput single-cell based, genome-wide gene silencing screening (sCRilecs-seq) revealed that drugging the mevalonate pathway resensitizes amoxicillin-resistant pneumococci.

Interactions between a mobile resistance gene and chromosomal mutations drive the evolution of high-level antibiotic resistance.

By binding with their type 1 pili to the cell surface receptor CD14, pathogenic E. coli suppress the capacity of dendritic cells to activate T cells.

The entry glycoproteins of hepatitis C virus, E1E2, possess a novel regulatory mechanism in which protein disorder is harnessed to control their activity and their ability to evade antibodies.

Nosocomial transmission of SARS-Cov-2 in geriatric settings is complex, with different patterns between patients and healthcare workers working in Covid/non-Covid wards that should be taken into account when designing infection control strategies.

Comprehensive mutational scanning of the SARS-CoV-2 protease, M^pro, provides functional and structural information to aid in the design of more effective inhibitors against the protease with reduced potential of evolving viral resistance.

Analyzing how mutations affect the main protease of SARS-CoV-2 may help researchers develop drugs that are effective against current and future variants of the virus.

Analysis of protein content and protein composition of the ChAdOx1 nCov-19 vaccine, but not of the Ad26.COV2.S vaccine, indicated significantly higher than expected levels of host cell proteins (HCPs) and of free viral proteins.

Fibronectin can shift from a globular to fibrillated form when adsorbing to implant surfaces, and this shift makes it accessible to attachment by Staphylococcus epidermidis, which is the leading cause of implant-associated infections.

A novel form of self-fertility evolved in Cryptococcus depauperatus, a close relative to the human pathogenic Cryptococcus species, in which sexual development is attained by self-signaling of a cognate pheromone and pheromone-receptor pair.