Browse our latest Microbiology and Infectious Disease articles

A multidisciplinary approach provides a description of the exocytic pathway that exports Salmonella Typhi's typhoid toxin from infected cells.

A newly developed computational framework provides an overview of the extent, diversity, and relevance of the genes of unknown function in genomes and metagenomes.

Membrane homeostasis in bacteria relies on the controlled degradation of endogenous phospholipids by intracellular phospholipases A, however their structures and catalytic mechanism are still poorly understood.

Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.

The HIV proteins Env and Rev encode helices that overlap in the viral genome but alternate in functional importance so that the non-functional surface of one helix encodes the functional surface of the other.

Brucella facilitates its intracellular parasitism by hijacking the host-regulated IRE1α-dependent decay (RIDD)-BLOS1 innate immune defense system through the disassembly of the BLOC-1-related complex that results in the perinuclear trafficking of Brucella-containing vacuoles and enhanced susceptibility to infection.

RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.

Unique mechanisms of genetic exchange in the important protozoan pathogen Trypanosome cruzi were characterized in detail using genome analyses of hybrid clones at different time points, showing initial tetraploids followed by genome erosion.

Thousands of novel open-reading frames (ORFs) are translated in the bacterium Mycobacterium tuberculosis, including many short ORFs that are likely to contribute to cell fitness.

The bacterial pathogen Listeria monocytogenes requires respiration for the maintenance of cellular redox homeostasis.