Browse our latest Microbiology and Infectious Disease articles

Page 62 of 172
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid genome diversification

    Gabriel Machado Matos, Michael D Lewis ... Björn Andersson
    Unique mechanisms of genetic exchange in the important protozoan pathogen Trypanosome cruzi were characterized in detail using genome analyses of hybrid clones at different time points, showing initial tetraploids followed by genome erosion.
    1. Microbiology and Infectious Disease

    Pervasive translation in Mycobacterium tuberculosis

    Carol Smith, Jill G Canestrari ... Joseph T Wade
    Thousands of novel open-reading frames (ORFs) are translated in the bacterium Mycobacterium tuberculosis, including many short ORFs that are likely to contribute to cell fitness.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Listeria monocytogenes requires cellular respiration for NAD+ regeneration and pathogenesis

    Rafael Rivera-Lugo, David Deng ... Samuel H Light
    The bacterial pathogen Listeria monocytogenes requires respiration for the maintenance of cellular redox homeostasis.
    1. Microbiology and Infectious Disease

    Reconstitution of surface lipoprotein translocation through the Slam translocon

    Minh Sang Huynh, Yogesh Hooda ... Trevor F Moraes
    Slam is an outer membrane protein translocon that functions with the periplasmic chaperone Skp to translocate protein substrates across the outer membrane of Gram-negative cells.
    1. Microbiology and Infectious Disease

    Thermosynechococcus switches the direction of phototaxis by a c-di-GMP-dependent process with high spatial resolution

    Daisuke Nakane, Gen Enomoto ... Takayuki Nishizaka
    Colour-controlled c-di-GMP signalling mediates directional switch of phototaxis via within-a-pole regulation of type IV pili in rod-shaped cyanobacteria Thermosynechococcus vulcanus.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    History-dependent physiological adaptation to lethal genetic modification under antibiotic exposure

    Yuta Koganezawa, Miki Umetani ... Yuichi Wakamoto
    Single-cell time-lapse imaging and optogenetical gene recombination system uncovered that bacteria cells can overcome a deleterious genetic change of antibiotic resistance gene deletion depending on their environmental histories.
    1. Microbiology and Infectious Disease

    An Archaea-specific c-type cytochrome maturation machinery is crucial for methanogenesis in Methanosarcina acetivorans

    Dinesh Gupta, Katie E Shalvarjian, Dipti D Nayak
    A streamlined form of the bacterial System I cytochrome c biogenesis machinery in archaea was characterized using Methanosarcina acetivorans as a model system.
    1. Microbiology and Infectious Disease

    A LAMP sequencing approach for high-throughput co-detection of SARS-CoV-2 and influenza virus in human saliva

    Robert Warneford-Thomson, Parisha P Shah ... Roberto Bonasio
    COV-ID is a highly scalable technology that utilizes a two-step barcoding strategy to detect viral RNAs in saliva samples combining RT-LAMP, PCR, and next generation sequencing.
    1. Microbiology and Infectious Disease

    A novel lineage-tracing mouse model for studying early MmuPV1 infections

    Vural Yilmaz, Panayiota Louca ... Katerina Strati
    A novel mouse model which permits tracking of papillomavirus infected cells in mouse stratified epithelia during early infection by means of genetic reporter activation.
    1. Microbiology and Infectious Disease

    Intracellular glycosyl hydrolase PslG shapes bacterial cell fate, signaling, and the biofilm development of Pseudomonas aeruginosa

    Jingchao Zhang, Huijun Wu ... Luyan Ma
    A systematical study of pslG mutants at both a single cell and community level reveals the importance of intracellular glycosyl hydrolase PslG on the cell fate and biofilm development of P. aeruginosa, an opportunistic pathogen that can cause persistent infections.