Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Coordination of two opposite flagella allows high-speed swimming and active turning of individual zoospores

    Quang D Tran, Eric Galiana ... Xavier Noblin
    Coordinated actions of two opposite flagella control speed and change direction of plant pathogen Phytophthora zoospores, in which the anterior flagellum is the main motor to generate thrust and spontaneously switch from reciprocal beating to breaststrokes to reorient its body.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

    Michela Zaffagni, Jenna M Harris ... Sebastian Kadener
    In the context of SARS-CoV-2 infection, Nsp14 alters gene expression of the host cell through the interaction with the cellular enzyme IMPDH2.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Colicin E1 opens its hinge to plug TolC

    S Jimmy Budiardjo, Jacqueline J Stevens ... Joanna SG Slusky
    Bacterial warfare protein colicin E1 opens its hinge to plug antibiotic efflux pump TolC and potentiate antibiotics.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target

    Ujjwal Neogi, Nazif Elaldi ... Ali Mirazimi
    The interplay of the host metabolic reprogramming, its negative association with antiviral biological signaling pathways and the IFN-mediated host antiviral mechanism during Crimean–Congo hemorrhagic fever orthonairovirus (CCHFV) infection could provide attractive options for therapeutic intervention of CCHF.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins

    Paul Lambey, Omolade Otun ... Cédric Leyrat
    Experimentally validated structural models of ACKR1-LukE and CCR5-LukE complexes reveal the critical contributions of sulfotyrosine binding sites and divergent loops of Staphylococcus aureus leukotoxins to the recognition of chemokine receptors.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression

    Georgia M Cook, Katherine Brown ... Ian Brierley
    Combining ribosome profiling and RNA sequencing illuminates novel features of porcine reproductive and respiratory syndrome virus gene expression, including the regulation of polyprotein stoichiometry through temporal modulation of ribosomal frameshifting and the synthesis of non-canonical transcripts.
    1. Ecology
    2. Microbiology and Infectious Disease

    Competition for fluctuating resources reproduces statistics of species abundance over time across wide-ranging microbiotas

    Po-Yi Ho, Benjamin H Good, Kerwyn Casey Huang
    A simple model provides an accessible framework to infer macroscopic parameters of effective resource competition from longitudinal studies of microbial communities.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Viruses: A frameshift in time

    Martina M Yordanova, Pavel V Baranov
    The efficiency with which ribosomes shift reading frames when decoding viral RNA may change over the course of an infection.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement

    Kelsey Barrasso, Denise Chac ... Wai-Leung Ng
    A specific gut microbe Paracoccus aminovorans enhances host colonization of the human pathogen Vibrio cholerae by forming dual-species biofilm structures.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Agl24 is an ancient archaeal homolog of the eukaryotic N-glycan chitobiose synthesis enzymes

    Benjamin H Meyer, Panagiotis S Adam ... Helge C Dorfmueller
    The crenarchaeon Sulfolobus synthesizes the N-glycan core in the identical way as all Eukaryotes, which strengthens the hypothesis that the eukaryotic N-glycosylation is acquired from an ancient archaeon during eukaryogenesis.