Browse our latest Microbiology and Infectious Disease articles

Page 71 of 167
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural characterization of NrnC identifies unifying features of dinucleases

    Justin D Lormand, Soo-Kyoung Kim ... Holger Sondermann
    Dinucleases, specialized enzymes that catalyze the final step in RNA degradation, have evolved independently and repeatedly to fulfill essential roles in cell growth.
    1. Microbiology and Infectious Disease

    Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS

    Michael J Sheedlo, Clarissa L Durie ... Melanie D Ohi
    Structural analysis of the type IV secretion system purified from Legionella pneumophila uncovers new complex components and symmetry mismatches.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Adaptation and compensation in a bacterial gene regulatory network evolving under antibiotic selection

    Vishwa Patel, Nishad Matange
    Mutations in gene regulatory proteins set the stage for the evolution of antimicrobial resistance by shifting the fitness landscape of resistance-conferring mutations.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics

    Michael I Barton, Stuart A MacGowan ... P Anton van der Merwe
    Common variants of the SARS-CoV-2 Spike protein and its ligand, the human ACE2 receptor, increase the binding affinity, suggesting that they could increase viral transmissibility.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    A morphological transformation in respiratory syncytial virus leads to enhanced complement deposition

    Jessica P Kuppan, Margaret D Mitrovich, Michael D Vahey
    Respiratory syncytial virus produces filamentous particles that change shape when the viral matrix detaches from the viral membrane, and this change in shape results in enhanced deposition of complement proteins, with potential downstream consequences.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Misic, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities

    Swapnesh Panigrahi, Dorothée Murat ... Tâm Mignot
    A broadly applicable deep-learning based method that recognizes rod-shaped bacteria of virtually any species in complex bacterial communities.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants

    Elizabeth Jaworski, Rose M Langsjoen ... Andrew L Routh
    Tiled-ClickSeq provides a simple and novel next-generation sequencing approach for complete genome sequencing of viruses including SARS-CoV-2, whilst capturing RNA recombination events and minority variants.
    1. Microbiology and Infectious Disease

    PGFinder, a novel analysis pipeline for the consistent, reproducible, and high-resolution structural analysis of bacterial peptidoglycans

    Ankur V Patel, Robert D Turner ... Stéphane Mesnage
    PGFinder is an open-source software dedicated to the analysis of peptidoglycan mass spectrometry data that paves the way for peptidoglycomics.
    1. Microbiology and Infectious Disease

    Quantifying the relationship between SARS-CoV-2 viral load and infectiousness

    Aurélien Marc, Marion Kerioui ... Jeremie Guedj
    Viral dynamic modeling reveals the relationship between SARS-CoV-2 viral load and infectiousness and allows to anticipate the effects of variants of concern and of vaccination on transmission.
    1. Microbiology and Infectious Disease

    A Tad-like apparatus is required for contact-dependent prey killing in predatory social bacteria

    Sofiene Seef, Julien Herrou ... Tâm Mignot
    First identification of the molecular determinants driving contact-dependent predation in Myxococcus..