Browse our latest Neuroscience articles

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    1. Neuroscience

    Synaptic mechanisms of top-down control in the non-lemniscal inferior colliculus

    Hannah M Oberle, Alexander N Ford ... Pierre F Apostolides
    Optogenetic and electrophysiological experiments show how a behaviorally relevant 'feedback' pathway from auditory cortex controls neural activity in the inferior colliculus, an auditory midbrain region important for processing complex time-varying sounds such as speech.
    1. Neuroscience

    Increasing stimulus similarity drives nonmonotonic representational change in hippocampus

    Jeffrey Wammes, Kenneth A Norman, Nicholas Turk-Browne
    Hippocampal learning in dentate gyrus follows a U-shaped function, with moderate, but not high or low, overlap between representations leading to differentiation of neural patterns.
    1. Medicine
    2. Neuroscience

    The role of action potential changes in depolarization-induced failure of excitation contraction coupling in mouse skeletal muscle

    Xueyong Wang, Murad Nawaz ... Mark M Rich
    Detailed studies of excitation contraction coupling allowed determination of quantitative relationships between resting potential, generation of action potentials, conduction of action potentials, and generation of Ca2+ transients in individual mouse skeletal muscle fibers.
    1. Neuroscience

    The anterior cingulate cortex and its role in controlling contextual fear memory to predatory threats

    Miguel Antonio Xavier de Lima, Marcus Vinicius C Baldo ... Newton Sabino Canteras
    The anterior cingulate cortex provides predictive relationships between the context and the predator threat and influences the acquisition and expression of fear memory to predatory threat.
    1. Neuroscience

    Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons

    Seksiri Arttamangkul, Emily J Platt ... David Farrens
    Endogenous µ- and δ-opioid receptors do not form stable heterodimers in cholinergic interneurons.
    1. Neuroscience

    Ripples reflect a spectrum of synchronous spiking activity in human anterior temporal lobe

    Ai Phuong S Tong, Alex P Vaz ... Kareem A Zaghloul
    A continuum of ripple oscillations in human anterior temporal lobe reflects the dynamic synchrony of populations of neurons during memory retrieval.
    1. Neuroscience

    Presynaptic stochasticity improves energy efficiency and helps alleviate the stability-plasticity dilemma

    Simon Schug, Frederik Benzing, Angelika Steger
    Presynaptic plasticity in simulated neural networks with a simple biologically plausible learning rule improves metabolic efficiency and lifelong learning capabilities.
    1. Neuroscience

    Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons

    Xinyi Jenny He, Janki Patel ... Matthew R Banghart
    Mu and delta opioid receptors signal independently in hippocampal parvalbumin interneurons to regulate somato-dendritic excitability and synaptic transmission, with the delta opioid receptor dominating the response to enkephalin.
    1. Neuroscience

    Spatial tuning of face part representations within face-selective areas revealed by high-field fMRI

    Jiedong Zhang, Yong Jiang ... Sheng He
    Consistent spatial clustering and fine-scale neural tuning to different face parts were found within the face-processing regions, which may be the neural implementation of efficient neural computation for face identification.
    1. Neuroscience

    Partial connectomes of labeled dopaminergic circuits reveal non-synaptic communication and axonal remodeling after exposure to cocaine

    Gregg Wildenberg, Anastasia Sorokina ... Bobby Kasthuri
    3D serial electron microscopy reveals that individual dopamine axons in the nucleus accumbens contain different varicosity types based on their vesicle contents, rarely make synapses, and undergo major structural plasticity in response to cocaine.