Kee Wui Huang, Nicole E Ochandarena ... Bernardo L Sabatini
The dorsal raphe nucleus contains transcriptionally diverse cell classes that include subtypes of serotonergic neurons with distinct molecular and anatomical signatures.
Functional dissection of a cluster of male-specific neurons in Drosophila reveals a neuronal circuit regulating male courtship in accordance with the internal drive state.
Emil Dandanell Agerschou, Patrick Flagmeier ... Alexander K Buell
The high affinity α-synuclein-monomer binder AS69 converts into a strong sub-stoichiometric inhibitor of nucleation processes upon formation of the AS69-α-synuclein complex, achieving reduced aggregation in vitro and in vivo.
Adam Tuttle, Catherine M Drerup ... Alex V Nechiporuk
Long-range Ret receptor signaling promotes axon outgrowth and regulates growth cone dynamics in pioneer neurons by inducing transcriptional changes in Myosin-X expression.
Jada H Vaden, Gokulakrishna Banumurthy ... Jacques I Wadiche
The number of neurotransmitter vesicles released into the synaptic cleft is regulated by the size of the readily-releasable pool upstream of release probability.
Matthew R Nassar, Rasmus Bruckner, Michael J Frank
The P300, an electroencephalography (EEG) component known to be evoked by surprising events, predicts learning in a bidirectional manner that depends critically on the surrounding statistical context.
Francesco Tomassoni-Ardori, Gianluca Fulgenzi ... Lino Tessarollo
RbFox1 upregulation modulates the expression of hundreds of genes but only dysregulation of the TrkB.T1 receptor isoform expression causes BDNF-dependent LTP impairments.
Population response magnitude predicts how well an image will be remembered, in both monkey inferotemporal cortex and neural networks trained to categorize objects.
Thomas Michael Ernst, Anna Evelina Brol ... Dagmar Timmann
Pronounced cerebellar activation during unexpected omission of a potentially harmful event suggests that the cerebellum has to be added to the neural network processing prediction errors underlying emotional associative learning.