Browse our latest Neuroscience articles

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    1. Neuroscience

    A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective, and anti-inflammatory properties following status epilepticus in mice

    Lotfi Ferhat, Rabia Soussi ... Michel Khrestchatisky
    Pharmacologically induced hypothermia elicits anticonvulsant, neuroprotective, and anti-inflammatory properties.
    1. Neuroscience

    Layer 6 corticocortical neurons are a major route for intra- and interhemispheric feedback

    Simon Weiler, Manuel Teichert, Troy W Margrie
    Cortex-wide projections onto primary sensory and motor areas display substantial interhemispheric symmetry in their areal input identity and are primarily feedback in nature due to dominant inputs from Layer 6.
    1. Neuroscience

    Memory: Integrating past experiences

    Thomas MW Leir, Matthew PH Gardner
    New results help address a longstanding debate regarding which learning strategies allow animals to anticipate negative events based on past associations between sensory stimuli.
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    1. Neuroscience

    Auditory cortex anatomy reflects multilingual phonological experience

    Olga Kepinska, Josue Dalboni da Rocha ... Narly Golestani
    Multilingual experience, particularly with larger phonological inventories across multilinguals’ languages, is linked to structural differences in transverse temporal gyri, highlighting experience-driven plasticity as a key factor shaping auditory cortex anatomy.
    1. Cell Biology
    2. Neuroscience

    Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease

    Vibhavari Aysha Bansal, Jia Min Tan ... Toh Hean Ch'ng
    Characterization of nuclear pore loss and dysfunction in nucleocytoplasmic compartmentalization in Alzheimer's disease neurons.
    1. Neuroscience
    2. Computational and Systems Biology

    Fast and slow synaptic plasticity enables concurrent control and learning

    Brendan A Bicknell, Peter E Latham
    Not revised
    Reviewed Preprint v1
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    1. Neuroscience

    Spatial localization of hippocampal replay requires dopamine signaling

    Matthew R Kleinman, David J Foster
    Hippocampal replay, which is implicated in memory formation and planning, exhibits a reward-dependent spatial specificity that in novel environments requires dopamine signaling.
    1. Neuroscience

    The neural correlates of novelty and variability in human decision-making under an active inference framework

    Shuo Zhang, Yan Tian ... Haiyan Wu
    Neurobehavioral data combined with computational models shows the superiority of active inference models in explaining human decisions under uncertainty.
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    A multiomic study reveals the role of ZFHX3 transcription factor in daily timekeeping with a combination of transcription factor and histone ChIP-seq and time-resolved RNA-seq in the mammalian central clock.
    1. Neuroscience

    Two long-axis dimensions of hippocampal-cortical integration support memory function across the adult lifespan

    Kristin Nordin, Robin Pedersen ... Alireza Salami
    Multimodal imaging reveals overlapping gradients of hippocampal connectivity reflecting patterns of cortical function, dopamine receptor distribution, and individual differences in memory, with age-related dedifferentiation of gradient organization marking cognitive decline.