Browse our latest Neuroscience articles

Page 99 of 609
    1. Cancer Biology
    2. Neuroscience

    Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer

    Jeffrey Barr, Austin Walz ... Paola D Vermeer
    Nerve tracing and behavioral studies in tumor-bearing mice together with transcriptional and functional analysis reveal cancer-induced central and peripheral neuronal alterations that influence behavior.
    1. Neuroscience

    Sensitivity to vocal emotions emerges in newborns at 37 weeks gestational age

    Xinlin Hou, Peng Zhang ... Dandan Zhang
    Analysis of neonatal response reveals that at 37 weeks gestational age, infants exhibit a marked developmental shift in their ability to perceive emotional vocal prosody, highlighting a critical period for social emotional development with potential implications for early neurodevelopmental assessments.
    1. Neuroscience

    Mechanism of barotaxis in marine zooplankton

    Luis Alberto Bezares Calderón, Réza Shahidi, Gáspár Jékely
    Ciliated zooplankton larvae sense pressure by ciliary photoreceptor cells, which increase the beating of locomotor cilia via a serotonergic motor circuit leading to rapid upward swimming during barotaxis.
    1. Neuroscience

    Laminar specificity and coverage of viral-mediated gene expression restricted to GABAergic interneurons and their parvalbumin subclass in marmoset primary visual cortex

    Frederick Federer, Justin Balsor ... Alessandra Angelucci
    The gene-regulatory enhancers h56D and S5E2 restrict transgene expression to GABAergic and parvalbumin-positive interneurons, respectively, across marmoset cortical layers, thus representing a promising tool for circuit dissection in non-human primates.
    1. Neuroscience

    Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain

    Kevin C Lister, Calvin Wong ... Arkady Khoutorsky
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity

    Audrey T Medeiros, Scott J Gratz ... Kate M O'Connor-Giles
    In vivo analysis of endogenously tagged Ca2+ channel subunits reveals unexpected differences in subunit composition and synapse-specific relationships between channel abundance and synaptic strength.
    1. Neuroscience

    Cell-type-specific origins of locomotor rhythmicity at different speeds in larval zebrafish

    Moneeza A Agha, Sandeep Kishore, David L McLean
    Unexpected complexity in the synaptic basis of locomotor rhythmogenesis is linked to cell type and speed in larval zebrafish.
    1. Neuroscience

    DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response

    Ernie Yulyaningsih, Jung H Suh ... Pascal E Sanchez
    DNL343, a brain-penetrant integrated stress response inhibitor, reduces neurodegeneration in mouse models and identifies biomarker candidates for assessing treatment responses in clinical settings.
    1. Neuroscience

    Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure

    Stefan Passlick, Ghanim Ullah, Christian Henneberger
    Synaptic glutamate release is potentiated by short metabolic failure whereas longer durations of energy depletion lead to a postsynaptic failure of synaptic transmission.
    1. Neuroscience

    Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for normal breathing and chemosensory reflexes

    Yuan Chang, Savannah Lusk ... Russell S Ray
    Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for baseline breathing and hypercapnic, hypoxic chemosensory reflexes, which challenges the current understanding of central noradrenergic neurons in breathing control.