Browse our latest Physics of Living Systems articles

A microfluidic experimental approach combined with dynamical systems theory reveals how to entrain an embryonic oscillator, the segmentation clock, and allows for the quantification of its entrainment properties.

Biased growth of microtubules in the advancing axon tip contributes to the uniform orientation of microtubules in mature axons, which is essential for proper neuronal functioning.

A light-controllable ligand is used to probe where in the signaling cascade T cells discriminate self from non-self.

A tracking animal's decision to intermittently pause and sniff the air reflects its belief that it is far downwind of the odor source, where benefits of sensing rare airborne cues outweigh the cost of pausing.

Computational model reveals why pausing to sniff the air helps animals track a scent when they are far away from the source.

Computational evolutionary model to predict the efficacy of broadly neutralizing antibodies (bNAbs) in suppressing HIV and to design optimal combination therapy with bNAbs.

Tracking proteins in live cells is challenging due to technical limitations and biological complexity, but approaches based in Bayesian nonparametrics stand a decent chance at recovering a target protein's dynamic profile from noisy data.

The emergent organization of bacterial proteomes—the integration of proteins into collective networks that encode function—can be defined purely from spectral analysis of ortholog covariation across extant diversity.

The volume of the nucleus is dictated by a balance of colloid osmotic forces from the nucleoplasm and cytoplasm.

A biophysical model in which kinetochore microtubules nucleate at kinetochores and growth polward along nematic streamlines quantitatively explains kinetochore microtubule lengths, orientations, and spatially varying dynamics in metaphase human spindles.