Browse our latest Physics of Living Systems articles

Page 26 of 54
    1. Neuroscience
    2. Physics of Living Systems

    Sensing complementary temporal features of odor signals enhances navigation of diverse turbulent plumes

    Viraaj Jayaram, Nirag Kadakia, Thierry Emonet
    Effective navigation of odor plumes in the wild requires that animals sense multiple temporal aspects of odor signals, which are encoded naturally by neurons in the fly olfactory circuit.
    1. Biochemistry and Chemical Biology
    2. Physics of Living Systems

    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity

    Rebecca LaCroix, Benjamin Lin ... Andre Levchenko
    The regulatory subunit of protein kinase A (PKA) can both activate and suppress the PKA activity at the plasma membrane, with its graded membrane localization capable of inducing a switch in cell migration.
    1. Developmental Biology
    2. Physics of Living Systems

    Emergence of a geometric pattern of cell fates from tissue-scale mechanics in the Drosophila eye

    Kevin D Gallagher, Madhav Mani, Richard W Carthew
    Formation of a triangular lattice of photoreceptor clusters in the compound eye is driven by highly regulated cell flows in the eye epithelium, through a mechanochemical mechanism.
    1. Physics of Living Systems

    Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law

    Thomas C Day, Stephanie S Höhn ... Peter J Yunker
    The distributions of cellular neighborhood volumes in two very different multicellular species - snowflake yeast and Volvox carteri - are found to obey a common functional form arising from maximum entropy consideration, despite great differences in their cell division processes.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    An empirical energy landscape reveals mechanism of proteasome in polypeptide translocation

    Rui Fang, Jason Hon ... Ying Lu
    Empirical energy landscape allows simulating the structural dynamics of the proteasomal ATPase complex, which yields predictions that are widely consistent with experimental observations and reveals the functional mechanism of the proteasome in substrate degradation.
    1. Cell Biology
    2. Physics of Living Systems

    Correlative all-optical quantification of mass density and mechanics of subcellular compartments with fluorescence specificity

    Raimund Schlüßler, Kyoohyun Kim ... Jochen Guck
    The combination of optical diffraction tomography and Brillouin microscopy in a single setup enables to quantitatively map the viscoelastic properties of cellular compartments such as aggregates and stress granules in vivo.
    1. Cell Biology
    2. Physics of Living Systems

    Volume growth in animal cells is cell cycle dependent and shows additive fluctuations

    Clotilde Cadart, Larisa Venkova ... Marco Cosentino Lagomarsino
    High-throughput measurement of single-cell volume reveals the short and large timescale fluctuation patterns of animal cell volume growth.
    1. Physics of Living Systems

    Emergence of behaviour in a self-organized living matter network

    Philipp Fleig, Mirna Kramar ... Karen Alim
    Behavioural states emerge from variability in the complexity of underlying active contraction dynamics in a single-cell, network-shaped forager.
    1. Neuroscience
    2. Physics of Living Systems

    A theory of synaptic transmission

    Bin Wang, Olga K Dudko
    The analytic theory establishes the general principles of synaptic transmission, enables extraction of microscopic parameters of synaptic fusion machinery from experiments, and links molecular constituents to synaptic function.
    1. Physics of Living Systems

    Strong confinement of active microalgae leads to inversion of vortex flow and enhanced mixing

    Debasmita Mondal, Ameya G Prabhune ... Prerna Sharma
    Coupling between cell motility and strong confinement alters the force generators that cause flow fields to change their handedness and lead to enhanced mixing.