Browse our latest Physics of Living Systems articles

Page 29 of 58
    1. Physics of Living Systems

    Humans optimally anticipate and compensate for an uneven step during walking

    Osman Darici, Arthur D Kuo
    Humans can predict and optimally plan goal-directed dynamic walking tasks that have transient events such as negotiating a sidewalk curb.
    1. Physics of Living Systems

    Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor

    Weikang Wang, Dante Poe ... Jianhua Xing
    Integrated live cell imaging and image analyses in the framework of transition path theories identify epithelial-to-mesenchymal transition proceeds through parallel paths.
    1. Evolutionary Biology
    2. Physics of Living Systems

    In vivo intraoral waterflow quantification reveals hidden mechanisms of suction feeding in fish

    Pauline Provini, Alexandre Brunet ... Sam Van Wassenbergh
    The integration of biplanar X-ray videos with 3D X-ray particle tracking revealed that fish use a combination of intraoral 'central jet' waterflow pattern and inertia to guide food toward the digestive tract during suction feeding.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Chemotactic smoothing of collective migration

    Tapomoy Bhattacharjee, Daniel B Amchin ... Sujit Sankar Datta
    Studies of bacterial chemotaxis reveal how limitations in single-cell sensing of stimuli influence large-scale population morphology.
    1. Developmental Biology
    2. Physics of Living Systems

    Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination

    Hanqing Guo, Michael Swan, Bing He
    Combined optogenetic and computer modeling approaches reveal how mechanical bistability of the mesoderm epithelium works jointly with apical constriction to facilitate mesoderm invagination in Drosophila, a well-characterized model for epithelial folding.
    1. Developmental Biology
    2. Physics of Living Systems

    Tissue Organization: When cells get in the flow

    Giovanna M Collu, Marek Mlodzik
    New imaging approaches question a long-standing model for how the eyes of fruit flies acquire their geometric patterning.
    Version of Record
    Insight
    1. Physics of Living Systems

    Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies

    Luke K Davis, Ian J Ford, Bart W Hoogenboom
    Computational modelling predicts spatial segregation of different types of nuclear transport receptors in assemblies of nuclear pore proteins, lending support to the idea of separate transport pathways in the nuclear pore complex as a way to enhance transport efficiency.
    1. Physics of Living Systems

    Learning developmental mode dynamics from single-cell trajectories

    Nicolas Romeo, Alasdair Hastewell ... Jörn Dunkel
    A computational framework enables the inference of hydrodynamic continuum models for collective cell migration from live-cell imaging data recorded in zebrafish embryos.
    1. Neuroscience
    2. Physics of Living Systems

    Sensing complementary temporal features of odor signals enhances navigation of diverse turbulent plumes

    Viraaj Jayaram, Nirag Kadakia, Thierry Emonet
    Effective navigation of odor plumes in the wild requires that animals sense multiple temporal aspects of odor signals, which are encoded naturally by neurons in the fly olfactory circuit.
    1. Biochemistry and Chemical Biology
    2. Physics of Living Systems

    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity

    Rebecca LaCroix, Benjamin Lin ... Andre Levchenko
    The regulatory subunit of protein kinase A (PKA) can both activate and suppress the PKA activity at the plasma membrane, with its graded membrane localization capable of inducing a switch in cell migration.